Gene: WDR19

Basic information

Tag Content
Uniprot ID I3LLZ8
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000025118
Ensembl nucleotide ID ENSSSCG00000008789
Gene name WD repeat domain 19
Gene symbol WDR19
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MKRVFTLLEK TWLGTPIWFT WQKTSGNYLA VTGADHIVKI FDRHGQQRSE INLSGNCVAM 60
DWDKDGDILA VIAEKSSYIY LWDANTNKTS QLDSGMRDQM SFLLWSKFGS FLAVGTVKGN 120
LLIYNRQTSR KIPVLGKHTK RITCGCWNAE NMLALGGEDK MITVSNQEGD TIRQTPVRSE 180
PSDMQFSMMK TDDRTSAAES TISVVVGKKT LFLFNLSEPD NPIDLEFQQQ YGNIVCYSWY 240
GDGYIMIGFS RGIFVVISTH VREIGQEIFQ ARDHKDSLTS IAVSQTLNKA ATCGDNCIKI 300
HDLADLKDMY AIINLDDENK GLGTLSWTED GQLLALSTQS GSLHVFLTKL PILGDACSTR 360
IAYLTSLLEV TVANPVEGEL PVTVSVHVEP NFVAVGLYHL AVGMNNRAWF YVLEENAVKK 420
LKDMEYLGTV ASICLHSDYA AALFEGKVQL HLIESEVLDA QEERETRLFP AVDDKCRILC 480
HALTSDFLIY GTDTGVIQYF YIEDWQFVND YRHPVGVKKI FPDPNGTRLV FIDEKSEGFV 540
YCPVKDATYE IPDFPPTIKG VLWENWPVDK GVFIAYDDDK VYTYVFHKDT IQGSKVILAG 600
GTKVPFSHKP LLLYNGELTC QTQSGKINNI YLSTHSFLES LKDMGTNERR QMLTQTLMLK 660
RFPDAWEVCK ILNDHAAWNE LARACLYHME VEFAIRVYRT IGNVGMVMSL EQIKGIEDCH 720
LLAGHLAMFT SDFNLAQDLY LASSCPVAAL EMRRDLQHWD SALQLAKRLA PDQIPFISKE 780
YAIQLEFTGD YVNALAHYEK GITGDNKEHD EVCLAGIAQM SIRMGDIRRG VSQALKHPSR 840
VLKRDCGAIL ENMKQFSEAA QLYEKGLYYD KAASVYIRCK NWAKVGELLP HVSSPKIHLQ 900
FAKAKEADGR YKEAVVAYEN AKQWNSVIRI YLDHLNNPEK AVRIVRETQS LDGAKMVARF 960
FLQLGDYGSA IQFLVMSKCN NEAFTLAQQH NKMEIYVDVI GSGDTTNEDY QSIALYFEGE 1020
KRHFQAGKFF LLCGQYARAL KHFLKCPNSE DNAALEMAIE TVGQAKDDVL TSQLIDHLMG 1080
ESDGMPKDAK YLFRLYMALK QYREAARTAI IIAREEQSAG NYRNAHDVLF SMYAELKAQK 1140
IKIPSEMATN LMILHSYILV KIHVKNGDHM KGARMLIRVA NNISKFPSHI VPILTSTVIE 1200
CHRAGLKNSA FSFAATLMRP EYRNKIDAKY KKKIEAMVRR PDTSETEEAT TPCPFCEFLL 1260
PECELLCPGC KNNIPYCIAT GRHMLKDDWT VCPHCDFPAL YSEFKRMLNT ERTCPMCSER 1320
LNLAQLKKIS DYTQYLQTEV EQ 1342

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologWDR19A0A452EI70Capra hircusPredictionMore>>
1:1 orthologWDR1957728Q8NEZ3Homo sapiensPredictionMore>>
1:1 orthologWdr19213081Q3UGF1CPO,CLPMus musculusPublicationMore>>
1:1 orthologWDR19461172H2QPC5Pan troglodytesPredictionMore>>
1:1 orthologWDR19I3LLZ8Sus scrofaPredictionMore>>
1:1 orthologWDR19100352314G1SME2Oryctolagus cuniculusPredictionMore>>
1:1 orthologWdr19305349F1LV01Rattus norvegicusPredictionMore>>
1:1 orthologwdr19E7FGG5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005929 cilium
GO:0030991 intraciliary transport particle A
GO:0031514 motile cilium
GO:0032391 photoreceptor connecting cilium
GO:0000902 cell morphogenesis
GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway
GO:0060271 cilium assembly
GO:0055123 digestive system development
GO:0042471 ear morphogenesis
GO:0031076 embryonic camera-type eye development
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0030326 embryonic limb morphogenesis
GO:0008406 gonad development
GO:0001701 in utero embryonic development
GO:0035721 intraciliary retrograde transport
GO:0061055 myotome development
GO:0050877 nervous system process
GO:1903441 protein localization to ciliary membrane
GO:0065003 protein-containing complex assembly
GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0853 WD repeat

Interpro

InterPro ID InterPro Term
IPR011990 TPR-like_helical_dom_sf
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR040379 WDR19/dyf-2
IPR039468 WDR19_WD40_rpt

PROSITE

PROSITE ID PROSITE Term
PS50294 WD_REPEATS_REGION

Pfam

Pfam ID Pfam Term
PF15911 WD40_3