| Tag | Content |
|---|---|
| Uniprot ID | F1LV01 |
| Entrez ID | 305349 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001191679.2 |
| Ensembl protein ID | ENSRNOP00000003991 |
| Ensembl nucleotide ID | ENSRNOG00000002932 |
| Gene name | WD repeat domain 19 |
| Gene symbol | Wdr19 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MKRVFSLLEK TWLGAPIQFA WQKSSGNYLA VTGADSVVKI FDRHGQKRSE ISLPGNCVAM 60 DWDKDGDILA VIAEKSSCIY LWDANTNKTS QLDNGMRDQM SFLLWSKIGS FLAVGTIKGN 120 LLIYNHQTSR KIPVLGKHTK KITCGCWNTE NLLALGGEDR MITVSNQEGD TIRQTPVKSE 180 PSDIKFSTSK TDERISSAES TISAVVGKKM LFLFHLNEPD NPVDLEFQQA YGNIVCYSWY 240 GDGYIMIGFS RGTFLAISTH FPEVGQEIFK TRDHKDNLTS VALSQTLNKA ATCGDNCIKI 300 HDLTELRDMY AIINLDDENK GLGTLSWTDD GQLLALSTQR GSLHVFLTKL PILGDACHTR 360 IAYLTSLLEV TVANLIEGEP PITVSVDVEP NFVAVGLYHL AVGMNNRAWF YVLGENVVKK 420 LKDVEYLGTV ASICLHSDYA AALFEGKIQL HLIENEMLDA QEERETRLFP AVDDKCRILC 480 HALTSDFLIY GTDTGIIQYF FIEDWQFVND YRHPVGVKKL FPDPNGTRLV FIDEKSDGFV 540 YCPVNDATYE IPDFSPTIKG VLWENWPMDK GVFIAYDDDK VYTYVFHKDT IQGSKVILAG 600 GTKLPFSHKP LLLYNGELTC QTQSGKINSI YLSTHSFLDS VKDTEPPDLR QMLMQTLMLK 660 RFPDAWDICK MLNDRTSWSE LARACLHHME VEFAIRVSRT MGDVGTVMSL EQIKGIEDYN 720 LLAGHLAMFT NDFNLAQDLY LASNCPVAAL EMRRDLQHWD SALQLAKRLA PDQIPFISKE 780 YAIQLEFTGD YVNALAHYEK GITGDNKEHD EVCLAGVAQM SIRMGDIRRG ANQALKHPSR 840 VLKRDCGAIL ENMKQFSEAA QLYEKGQYYD RAASVYIRCK NWAKVGELLP HVSSPKIHLQ 900 YAKAKEADGR YKEAVVAYEN AKQWNSVIRI YLDHLNNPEK AVSIVRETQS LDGAKMVARF 960 FLQLGDYGSA IQFLVLSKCN NEAFTLAQQH NKMEIYADII GAEDTTNEDY QSIALYFEGE 1020 KRHFQAGKFF LLCGQYSRAL KHFLKCPSSE DNVAIEMAIE TVGQAKDELL TNQLIDHLMG 1080 ESDGMPKDAK YLFRLYMALK QYREAARTAI IIAREEQSAG NYRNAHDVLF SMYAELKSQK 1140 IKIPSEMATN LMILHSYILV KIHVKSGDHM KGARMLIRVA NNISKFPSHI VPILTSTVIE 1200 CHRAGLKNSA FSFAAMLMRP EYRNKIDAKY KKKIEAMVRR PDTSETEEAT TPCPFCQFLL 1260 PECELLCPGC KNNIPYCIAT GRHMLKDDWT MCPHCGFPAL YSEFKILLNS ESTCPMCSER 1320 LNSSQLKKIT DCTQYLRTET E 1341 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | WDR19 | A0A452EI70 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | WDR19 | 57728 | Q8NEZ3 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Wdr19 | 213081 | Q3UGF1 | CPO,CLP | Mus musculus | Publication | More>> | |
| 1:1 ortholog | WDR19 | 461172 | H2QPC5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | WDR19 | I3LLZ8 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | WDR19 | 100352314 | G1SME2 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Wdr19 | 305349 | F1LV01 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | wdr19 | E7FGG5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005929 | cilium |
| GO:0030991 | intraciliary transport particle A |
| GO:0031514 | motile cilium |
| GO:0097730 | non-motile cilium |
| GO:0032391 | photoreceptor connecting cilium |
| GO:0000902 | cell morphogenesis |
| GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway |
| GO:0060271 | cilium assembly |
| GO:0055123 | digestive system development |
| GO:0042471 | ear morphogenesis |
| GO:0031076 | embryonic camera-type eye development |
| GO:0048701 | embryonic cranial skeleton morphogenesis |
| GO:0030326 | embryonic limb morphogenesis |
| GO:0008406 | gonad development |
| GO:0001701 | in utero embryonic development |
| GO:0035721 | intraciliary retrograde transport |
| GO:0061055 | myotome development |
| GO:0050877 | nervous system process |
| GO:1903441 | protein localization to ciliary membrane |
| GO:0065003 | protein-containing complex assembly |
| GO:0007224 | smoothened signaling pathway |
| GO:0060831 | smoothened signaling pathway involved in dorsal/ventral neural tube patterning |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50294 | WD_REPEATS_REGION |
| Pfam ID | Pfam Term |
|---|---|
| PF15911 | WD40_3 |