| Tag | Content |
|---|---|
| Uniprot ID | A0A452ELS6 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000012991 |
| Ensembl nucleotide ID | ENSCHIG00000014497 |
| Gene name | Integrin_alpha2 domain-containing protein |
| Gene symbol | ITGA5 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGSRTPGSPL HAVQLRRGAR RGPRLLPLLL LLLPPPPRVG GFNLDAEAPA VLSGPPGSFF 60 GFSVEFYRPG TDGVSVLVGA PKANTSQPGV LQGGAVYLCP WGTSPAQCTP IEFDSKGSRI 120 LESSTSSPEG EEPVEYKSLQ WFGATVRAHG SSILACAPLY SWRTEKEPQS DPVGTCYLST 180 GNFTRILEYA PCRSDFSQEA GQGYCQGGFS AEFTKTGRVV LGGPGSYFWQ GQILSATQEQ 240 IAESYYPGYL INPVRGQLQT RQASSIYDDS YLGYSVAVGE FSGDDREDFV AGVPKGNLTY 300 GYVTILNGSD IRSLYNFSGE QPNFSGSLES LTYPHSPLAA TDINGDGLDD LLVGAPLLME 360 RTADGRPQEV GRVYIYLQRL AGMEPMPTLT LTGQDEFGRF GSSLTPLGDL DQDGYNDVAI 420 GAAFGGENRQ GVVFIFPGGP GGLASKPSQV LLPLWAAGQT PDFFGSALRG GRDLDGNGYP 480 DLIVGSFGVD KAVVYRGRPI VSASASLTIF PAMFNPEEHS CSLEGNPVTC INLSFCLNAS 540 GKHVPDSIGF TVELQLDWQK QKGGVRRALF LASRQATLTQ TLLIQNGARE DCREMKIYLR 600 NESEFRDKLS PIHIALNFSL DPQAPVDSHG LRPVLHYQSK SRIEDKAQIL LDCGEDNICV 660 PDLQLEVFGE QNHVYLGDKN SLNLTFHAQN VGEGGAYEAE LRVTAPPEAE YSGLVRHPGN 720 FSSLSCDYFA VNQSRLLVCD LGNPMKAGAS LWGGLRFTVP HLRDTKKTIQ FDFQILSKNL 780 NNSQSDVVSF RLSVEAQAQV SLNGVSKPEA VLFPVSDWRP QDQPQEEGDV GPAVHHVYEL 840 INLGPSSISQ GVLELSCPHA LDGQQLLYVT RVTGLNNCTT SHPPNPEGLE LDPEGSQHHQ 900 LQRRDVPGRS PASSGPQILK CPEAECFKLR CELGPLHRQE SRSLQLHFRV WAKTFLQREH 960 QPFSLQCEAV YEALKMPYKI LPRQLPQKEL QVATAVQWIK AEGSHGVPLW IIILAILIGL 1020 LLLGLLIYIL YKLGFFKRSL PYGTAMEKAQ LKPPATSDA 1059 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ITGA5 | 486493 | F1PY05 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ITGA5 | A0A452ELS6 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ITGA5 | 3678 | P08648 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Itga5 | 16402 | P11688 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ITGA5 | A0A2I3RVI9 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | ITGA5 | 100155091 | F1SR53 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Itga5 | 315346 | A0A0G2K1E2 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0008305 | integrin complex |
| GO:0007155 | cell adhesion |
| GO:0007229 | integrin-mediated signaling pathway |