| Tag | Content |
|---|---|
| Uniprot ID | F1SR53 |
| Entrez ID | 100155091 |
| Genbank protein ID | HDA31027.1; HDA39892.1; HDA29379.1; HDA26363.1; HDB75663.1; HDB61898.1; HDA32060.1; HDA24142.1; HDA24141.1; HDA48082.1; HDB42929.1; |
| Genbank nucleotide ID | XM_001925252.6 |
| Ensembl protein ID | ENSSSCP00000000308 |
| Ensembl nucleotide ID | ENSSSCG00000000293 |
| Gene name | Integrin alpha-5 |
| Gene symbol | ITGA5 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGSRTPGSPL QAVQLRWGPR RRSRLLPLLP PPLLLLLLLP PPLRVGGFNL DAEAPAVLSG 60 PPGSFFGFSV EFYRPGTDGV SVLVGAPKAN TSQPGVLQGG AVYLCPWATS PAPCTPIEFD 120 SKGSRILESS PSSLEGDEPV EYKSLQWFGA TVRAHGSSIL ACAPLYSWRT EKEPLNDPVG 180 TCYLSTDNFT RILEYAPCRS DFSSAAGQGY CQGGFSAEFT KTGRVVLGGP GSYFWQGQIL 240 SATQEQISES YYPEYLINPV QGQLQTRQAS SIYDDSYLGY SVAVGEFSGD DTEDFVAGVP 300 KGNLTYGYVT ILNGSDIRSL YNFSGEQMAS YFGYAVAATD INGDGLDDLL VGAPLLMERT 360 ADGRPQEVGR VYIYLQSPAG MEPAPARTLT GHDEFGRFGS SLTPLGDLDQ DGYNDVAIGA 420 TFGGENRQGA VFIFPGGPEG LASKPSQVLQ PLWAAGHTPD FFGSALRGGR DLDGNGYPDL 480 IVGSFGVDKA VVYRGRPIVS ASASLSIFPA MFNPEERSCN LEGNPVACIN LSFCLNASGK 540 HVPDSIGFTV ELQLDWQKQK GGVRRVLFLA SRQATLTQTL LIQNGAREDC REMKIYLRNE 600 SEFRDKLSPI HIALNFSLDP QAPVDSHGLR PVLHYQSKSR IEDKAQILLD CGEDNICVPD 660 LQLEVFGDQN HVYLGDKNSL NLTFHAQNVG EGGAYEAELR VTAPPEAEYS GLVRHPGNFS 720 SLSCDYFAVN QSRLLVCDLG NPMKAGASLW SGLRFTVPHL RDTKKTIQFD FQILSKNLNN 780 SQSEVVSFRL SVEAQAQVSL NGVSKPEAVI FPVSDWHPRD PPQEEEDVGP AVHHVYELIN 840 LGPSSISRGV LELSCPQALE GRQLLYVTRV TGLSNCTTSH PLNPQGLELD PESPQHHRLQ 900 RRDAASRSPA SSGPQILKCP EAECFRLRCE LGPLHRQESR SLQLHFRVWA KTFLQREHQP 960 FSLQCEAVYQ ALKMPYRILP RQLPQKELQV ATAVQWIKAE GSHGVPLWII ILAILVGLLL 1020 LGLLIYILYK LGFFKRSLPY GTAMEKAQLK PPATSDA 1057 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ITGA5 | 486493 | F1PY05 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ITGA5 | A0A452ELS6 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ITGA5 | 3678 | P08648 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Itga5 | 16402 | P11688 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ITGA5 | A0A2I3RVI9 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | ITGA5 | 100155091 | F1SR53 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Itga5 | 315346 | A0A0G2K1E2 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005911 | cell-cell junction |
| GO:0031410 | cytoplasmic vesicle |
| GO:0005783 | endoplasmic reticulum |
| GO:0009897 | external side of plasma membrane |
| GO:0005925 | focal adhesion |
| GO:0005794 | Golgi apparatus |
| GO:0034674 | integrin alpha5-beta1 complex |
| GO:0032587 | ruffle membrane |
| GO:0045202 | synapse |
| GO:0005178 | integrin binding |
| GO:0023035 | CD40 signaling pathway |
| GO:0033631 | cell-cell adhesion mediated by integrin |
| GO:0031589 | cell-substrate adhesion |
| GO:0007044 | cell-substrate junction assembly |
| GO:0035987 | endodermal cell differentiation |
| GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules |
| GO:0034113 | heterotypic cell-cell adhesion |
| GO:0007229 | integrin-mediated signaling pathway |
| GO:0007159 | leukocyte cell-cell adhesion |
| GO:0007613 | memory |
| GO:2000811 | negative regulation of anoikis |
| GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation |
| GO:1903672 | positive regulation of sprouting angiogenesis |
| GO:0035313 | wound healing, spreading of epidermal cells |