Gene: NXN

Basic information

Tag Content
Uniprot ID A0A452F4G8
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000019061
Ensembl nucleotide ID ENSCHIG00000018214
Gene name Thioredoxin domain-containing protein
Gene symbol NXN
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
IFIMLLRDSL KLWNKYRISN IPSLIFLDAT SGKVVCRNGL LVIRDDPEGL EFPWGPKPFR 60
EVIAGSLLRN NGQSLESSSL EGSHVGVYFS AHWCPPCRSL TRVLVESYRK IKEAGQKFEI 120
IFVSADRSED SFKQYFSEMP WLAVPYTDEG RRSRLNRLYG IQGIPTLIVL DPQGEVITRQ 180
GRVEVLNDEE CRGFPWHPKP VLELSDSNAV QLNEGPCLVL FVDSEDDGES EAAKQLIQPI 240
AEKIIAKYKA KDEEAPLLFF VAGEDDMTDS LRDYTNLPEA APLLTILDMS ARAKYVMDVE 300
EITPAIVEAF VNDFLAEKLK PEPI 324

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologNXN531367A6QLU8Bos taurusPredictionMore>>
1:1 orthologNXN611162J9NXW0Canis lupus familiarisPredictionMore>>
1:1 orthologNXNA0A452F4G8Capra hircusPredictionMore>>
1:1 orthologNXN64359Q6DKJ4Homo sapiensPredictionMore>>
1:1 orthologNxn18230P97346CPOMus musculusPublicationMore>>
1:1 orthologNXN746905K7DKH1Pan troglodytesPredictionMore>>
1:1 orthologNXNI3LEF2Sus scrofaPredictionMore>>
1:1 orthologNXN100338429G1SNE1Oryctolagus cuniculusPredictionMore>>
1:1 orthologNxn360577D4A0M2Rattus norvegicusPredictionMore>>
1:1 ortholognxnF1R5G2Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005623 cell
GO:0045454 cell redox homeostasis

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR041861 NRX_PDI_b
IPR012336 Thioredoxin-like_fold
IPR036249 Thioredoxin-like_sf
IPR013766 Thioredoxin_domain

PROSITE

PROSITE ID PROSITE Term
PS51352 THIOREDOXIN_2

Pfam

Pfam ID Pfam Term
PF13905 Thioredoxin_8