| Tag | Content |
|---|---|
| Uniprot ID | G1SNE1 |
| Entrez ID | 100338429 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_002718895.2 |
| Ensembl protein ID | ENSOCUP00000004496 |
| Ensembl nucleotide ID | ENSOCUG00000005189 |
| Gene name | Thioredoxin domain-containing protein |
| Gene symbol | NXN |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSGFLEELLG EKLVTGGGEE VDVHSLGARG ISLLGLYFGC SLSAPCAQLS ASLAAFYGRL 60 RGDAAAGPGA GPGPGAGAAA EPEPRSRLEI VFVSSDQDQR QWQDFVRDMP WLALPYKEKH 120 RKLKLWNKYR ISNIPSLIFL DATTGKVVCR NGLLVIRDDP EGLEFPWGPK PFREVIAGPL 180 LRNNGQSLES SSLEGSHVGV YFSAHWCPPC RSLTRVLVES YRKIKEAGQK FEIIFVSADR 240 SEESFKQYFS EMPWLAVPYT DEARRSRLNR LYGIQGIPTL IVLDPQGEVI TRQGRVEVLN 300 DEDCREFPWH PKPVLELSDS NAVQLNEGPC LVLFVDSEDD GESEAAKQLI QPIAEKVIAK 360 YKAKEEEAPL LFFVAGEDDM TDSLRDYTNL PEAAPLLTIL DMSARAKYVM DVEEITPAIV 420 EAFVNDFLAE KLKPEPI 437 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NXN | 531367 | A6QLU8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | NXN | 611162 | J9NXW0 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | NXN | A0A452F4G8 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | NXN | 64359 | Q6DKJ4 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Nxn | 18230 | P97346 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | NXN | 746905 | K7DKH1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | NXN | I3LEF2 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | NXN | 100338429 | G1SNE1 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Nxn | 360577 | D4A0M2 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | nxn | F1R5G2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005623 | cell |
| GO:0045454 | cell redox homeostasis |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51352 | THIOREDOXIN_2 |
| Pfam ID | Pfam Term |
|---|---|
| PF13905 | Thioredoxin_8 |