| Tag | Content |
|---|---|
| Uniprot ID | A0A452FFP9 |
| Entrez ID | 102179885 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018066420.1 |
| Ensembl protein ID | ENSCHIP00000023000 |
| Ensembl nucleotide ID | ENSCHIG00000020729 |
| Gene name | Aldedh domain-containing protein |
| Gene symbol | ALDH1A3 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MATTNGAVEN GQPDRKAPAL PRPVRNLEVQ FTKIFINNEW NESKSGKKFA TYNPSTLEKI 60 CEVEEGDKPD VDKAVEAAQA AFQRGSPWRR LDAPSRGRLL QQLADLVERD RAVLATLETM 120 DTGKPFLHAF FIDLEGCIKT LRYFAGWADK IQGRTIPTDD NVVCFTRHEP IGVCGAITPW 180 NFPLLMLVWK LAPALCCGNT VVLKPAEQTP LTALYLGSLI KEVGFPPGVV NIVPGFGPTV 240 GAAISSHPQI NKIAFTGSTE VGKLVKEAAS HSNLKRVTLE LGGKNPCIVC ADADLSLAVE 300 CAHQGVFFNQ GQCCTAASRV FVEEQIYEEF VRQSVEYAKK RPVGDPFDVR TEQGPQIDQK 360 QFDKILDLIE SGKKEGAKLE CGGSAMEDRG LFIKPTVFSE VTDTMRIAKE EIFGPVQPIL 420 KFKNIEEVIK RANSLEYGLT AAVFTKNLDK ALKLASALES GTVWINCYNA IYAQAPFGGF 480 KMSGNGRELG EYALAEYTEV KTVTIKLDDK DP 512 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ALDH1A3 | 100856346 | E2R543 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ALDH1A3 | 102179885 | A0A452FFP9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ALDH1A3 | 100057072 | F6Y0Q6 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | ALDH1A3 | 220 | P47895 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Aldh1a3 | 56847 | Q9JHW9 | CPO,CLO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ALDH1A3 | 453686 | H2QA58 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ALDH1A3 | A0A480JMD7 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | G1SU45 | Oryctolagus cuniculus | Prediction | More>> | ||||
| 1:1 ortholog | Aldh1a3 | A0A0G2JUS6 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | aldh1a3 | 751785 | Q0H2G3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0004029 | aldehyde dehydrogenase (NAD+) activity |
| GO:0070403 | NAD+ binding |
| GO:0042803 | protein homodimerization activity |
| GO:0001758 | retinal dehydrogenase activity |
| GO:0070324 | thyroid hormone binding |
| GO:0060324 | face development |
| GO:0070384 | Harderian gland development |
| GO:0042472 | inner ear morphogenesis |
| GO:0007626 | locomotory behavior |
| GO:0050885 | neuromuscular process controlling balance |
| GO:0021768 | nucleus accumbens development |
| GO:0060166 | olfactory pit development |
| GO:0002072 | optic cup morphogenesis involved in camera-type eye development |
| GO:0043065 | positive regulation of apoptotic process |
| GO:0051289 | protein homotetramerization |
| GO:0042574 | retinal metabolic process |
| GO:0002138 | retinoic acid biosynthetic process |
| GO:0060013 | righting reflex |
| Pfam ID | Pfam Term |
|---|---|
| PF00171 | Aldedh |