| Tag | Content |
|---|---|
| Uniprot ID | H2QA58; A0A2J8L7L0; |
| Entrez ID | 453686 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_001142882.4 |
| Ensembl protein ID | ENSPTRP00000012824 |
| Ensembl nucleotide ID | ENSPTRG00000007508 |
| Gene name | Aldehyde dehydrogenase 1 family member A3 |
| Gene symbol | ALDH1A3 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MATTNGAVEN GQPDRKPPAL PRPIRNLEVK FTKIFINNEW HESKSGKKFA TCNPSTREQI 60 CEVEEGDKPD VDKAVEAAQV AFQRGSPWRR LDALSRGRLL HQLADLVERD RATLAALETM 120 DTGKPFLHAF FIDLEGCIRT LRYFAGWADK IQGKTIPTDD NVVCFTRHEP IGVCGAITPW 180 NFPLLMLVWK LAPALCCGNT MVLKPAEQTP LTALYLGSLI KEAGFPPGVV NIVPGFGPTV 240 GAAISSHPQI NKIAFTGSTE VGKLVKEAAS RSNLKRVTLE LGGKNPCIVC ADADLDLAVE 300 CAHQGVFFNQ GQCCTAASRV FVEEQVYSEF VRRSVEYAKK RPVGDPFDVK TEQGPQIDQK 360 QFDKILELIE SGKKEGAKLE CGGSAMEDKG LFIKPTVFSE VTDNMRIAKE EIFGPVQPIL 420 KFKSIEEVIK RANSTDYGLT AAVFTKNLDK ALKLASALES GTVWINCYNA LYAQAPFGGF 480 KMSGNGRELG EYALAEYTEV KTVTIKLGDK NP 512 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ALDH1A3 | 100856346 | E2R543 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ALDH1A3 | 102179885 | A0A452FFP9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ALDH1A3 | 100057072 | F6Y0Q6 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | ALDH1A3 | 220 | P47895 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Aldh1a3 | 56847 | Q9JHW9 | CPO,CLO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ALDH1A3 | 453686 | H2QA58 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ALDH1A3 | A0A480JMD7 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | G1SU45 | Oryctolagus cuniculus | Prediction | More>> | ||||
| 1:1 ortholog | Aldh1a3 | A0A0G2JUS6 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | aldh1a3 | 751785 | Q0H2G3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0004029 | aldehyde dehydrogenase (NAD+) activity |
| GO:0070403 | NAD+ binding |
| GO:0042803 | protein homodimerization activity |
| GO:0001758 | retinal dehydrogenase activity |
| GO:0070324 | thyroid hormone binding |
| GO:0060324 | face development |
| GO:0070384 | Harderian gland development |
| GO:0042472 | inner ear morphogenesis |
| GO:0007626 | locomotory behavior |
| GO:0050885 | neuromuscular process controlling balance |
| GO:0021768 | nucleus accumbens development |
| GO:0060166 | olfactory pit development |
| GO:0002072 | optic cup morphogenesis involved in camera-type eye development |
| GO:0043065 | positive regulation of apoptotic process |
| GO:0051289 | protein homotetramerization |
| GO:0042574 | retinal metabolic process |
| GO:0002138 | retinoic acid biosynthetic process |
| GO:0060013 | righting reflex |
| Pfam ID | Pfam Term |
|---|---|
| PF00171 | Aldedh |