Gene: aldh1a3

Basic information

Tag Content
Uniprot ID Q0H2G3
Entrez ID 751785
Genbank protein ID AAZ84926.1; ABC17784.1; ABP48748.1;
Genbank nucleotide ID NM_001044745.1
Ensembl protein ID ENSDARP00000055592
Ensembl nucleotide ID ENSDARG00000076933
Gene name Aldehyde dehydrogenase 1 family member A3
Gene symbol aldh1a3
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAQNGTIENG DSRNTSPPPL PQPVKITEIK HTKIFINNEW HTSSKGKQFP TINPATGVKI 60
CDIEEADKAD VDEAVKAAKA AGQRGSVWRR MDASSRGRLL NRLADLLERE RAVLATLESK 120
DTGKPFLHAF FVDLDGSIKT LRYYAGWTDK IHGKTMPVDE NFVCFTKHEP IGVCGAIIPW 180
NFPLLMLMWK IAPALACGNT VVLKPAEQTP LTALHVAALI KEAGFPPGVV NVVPGFGPTA 240
GAAIAGHMNI DKLAFTGSTE VGQLVKAAAA SSNLKRVTLE LGGKNPCIVF ADSDLQLAVE 300
ETQKGAFFNQ GQACTAASRV YVQEPVYEEF VRLSVERAKN IVIGDPMEPR TSHGPQIDQH 360
QFEKILALVD SGKKEGAKLE FGGCAVEDRG LFIHPTIFSD VKDHMRIAKE EIFGPVQCIM 420
KFECQQDVID RANSSQFGLT AAVFTRDVQR AMSVSAALEA GTVWVNCYNA LHAQTPFGGY 480
KMSGNGRELG EYALAEYTEV KAITIKLSEQ LRL 513

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologALDH1A3100856346E2R543Canis lupus familiarisPredictionMore>>
1:1 orthologALDH1A3102179885A0A452FFP9Capra hircusPredictionMore>>
1:1 orthologALDH1A3100057072F6Y0Q6Equus caballusPredictionMore>>
1:1 orthologALDH1A3220P47895Homo sapiensPredictionMore>>
1:1 orthologAldh1a356847Q9JHW9CPO,CLOMus musculusPublicationMore>>
1:1 orthologALDH1A3453686H2QA58Pan troglodytesPredictionMore>>
1:1 orthologALDH1A3A0A480JMD7Sus scrofaPredictionMore>>
1:1 orthologG1SU45Oryctolagus cuniculusPredictionMore>>
1:1 orthologAldh1a3A0A0G2JUS6Rattus norvegicusPredictionMore>>
1:1 orthologaldh1a3751785Q0H2G3Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0004029 aldehyde dehydrogenase (NAD+) activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0560 Oxidoreductase
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR016160 Ald_DH_CS_CYS
IPR029510 Ald_DH_CS_GLU
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom

PROSITE

PROSITE ID PROSITE Term
PS00070 ALDEHYDE_DEHYDR_CYS
PS00687 ALDEHYDE_DEHYDR_GLU

Pfam

Pfam ID Pfam Term
PF00171 Aldedh