Gene:

Basic information

Tag Content
Uniprot ID G1SU45
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSOCUP00000006861
Ensembl nucleotide ID ENSOCUG00000007938
Gene name Aldedh domain-containing protein
Gene symbol
Organism Oryctolagus cuniculus
NCBI taxa ID 9986
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MATTNGAVEN GQPDKKAPVL PRPVRNLEVK FTKIFINNEW HQSKSGKKFA TYNPSTLEKI 60
CDVEEGDKPD VDKAVEAAQA AFQRGSPWRR LDALSRGRLL QQLADLVERD RAVLATLETM 120
DTGKPFLHAF FIDLEGCIKT LRYFAGWADK IQGRTIPTDD NVLCFTRHEP VGVCGAITPW 180
NFPLLMLVWK LAPALCCGNT VVLKPAEQTP LTALHLGSLI KEVGFPPGVV NIVPGFGPTV 240
GAAISSHPQI NKIAFTGSTE VGKLVKEAAS RSNLKRVTLE LGGKNPCIVC ADADLDLAVE 300
CAHQGVFFNQ GQCCTAASRV FVEEQVYPEF VKRSVEYAKK RPVGDPFDVK TEQGPQIDQK 360
QFNKILELIE SGKQEGAKLE CGGSAVEDRG LFITPTVFSE VTDSMRIAKE EIFGPVQPIL 420
KFKNLEEVIK RANSTDYGLT AAVFTKNLDK ALKLASALES GTVWINCYNA LYAQAPFGGF 480
KMSGNGREL 489

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologALDH1A3100856346E2R543Canis lupus familiarisPredictionMore>>
1:1 orthologALDH1A3102179885A0A452FFP9Capra hircusPredictionMore>>
1:1 orthologALDH1A3100057072F6Y0Q6Equus caballusPredictionMore>>
1:1 orthologALDH1A3220P47895Homo sapiensPredictionMore>>
1:1 orthologAldh1a356847Q9JHW9CPO,CLOMus musculusPublicationMore>>
1:1 orthologALDH1A3453686H2QA58Pan troglodytesPredictionMore>>
1:1 orthologALDH1A3A0A480JMD7Sus scrofaPredictionMore>>
1:1 orthologG1SU45Oryctolagus cuniculusPredictionMore>>
1:1 orthologAldh1a3A0A0G2JUS6Rattus norvegicusPredictionMore>>
1:1 orthologaldh1a3751785Q0H2G3Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0560 Oxidoreductase
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR016160 Ald_DH_CS_CYS
IPR029510 Ald_DH_CS_GLU
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom

PROSITE

PROSITE ID PROSITE Term
PS00070 ALDEHYDE_DEHYDR_CYS
PS00687 ALDEHYDE_DEHYDR_GLU

Pfam

Pfam ID Pfam Term
PF00171 Aldedh