Gene: WNT6

Basic information

Tag Content
Uniprot ID A0A452FTD5
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000027521
Ensembl nucleotide ID ENSCHIG00000023410
Gene name Protein Wnt
Gene symbol WNT6
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description Ligand for members of the frizzled family of seven transmembrane receptors.
Sequence
MSQLPAISWA GAVGSPLVMD PTSICRKARR LAGRQAELCQ AEPEVVAELA RGARLGVREC 60
QFQFRFRRWN CSSHSKAFGR ILQQDIRETA FVFAITAAGA SHAVTQACSM GELLQCGCQA 120
PRGRAPPRPP GLPGTPGPPG PAGSPDGSAA WEWGGCGDDV DFGDEKSRLF MDAQHKRGRG 180
DIRMLVQLHN NEAGRLAVRS HTRTECKCHG LSGSCALRTC WQKLPPFREV GARLLERFHG 240
ASRVMGTNDG KALLPAVRTL KPPGRADLLY AADSPDFCAP NRRTGSPGTR GRACNSSAPD 300
LSGCDLLCCG RGHRQESVLL EENCLCRFHW CCVVQCHRCR VRKELSLCL 349

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologWNT6505075F1MN70Bos taurusPredictionMore>>
1:1 orthologWNT6A0A452FTD5Capra hircusPredictionMore>>
1:1 orthologWNT67475Q9Y6F9Homo sapiensPublicationMore>>
1:1 orthologWnt622420P22727E14.5Mus musculusPredictionMore>>
1:1 orthologWNT6742467A0A2I3SR43Pan troglodytesPredictionMore>>
1:1 orthologWNT6A0A287BRH3Sus scrofaPredictionMore>>
1:1 orthologWNT6G1TQH3Oryctolagus cuniculusPredictionMore>>
1:1 orthologWnt6316526D4A3W9Rattus norvegicusPredictionMore>>
1:1 orthologwnt6bF1RAB5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005576 extracellular region
GO:0005102 signaling receptor binding
GO:0007275 multicellular organism development
GO:0016055 Wnt signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0217 Developmental protein
KW-1015 Disulfide bond
KW-0272 Extracellular matrix
KW-1185 Reference proteome
KW-0964 Secreted
KW-0879 Wnt signaling pathway

Interpro

InterPro ID InterPro Term
IPR005817 Wnt
IPR009143 Wnt6
IPR043158 Wnt_C
IPR018161 Wnt_CS

PROSITE

PROSITE ID PROSITE Term
PS00246 WNT1

Pfam

Pfam ID Pfam Term
PF00110 wnt