Gene: wnt6b

Basic information

Tag Content
Uniprot ID F1RAB5
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSDARP00000113576
Ensembl nucleotide ID ENSDARG00000073935
Gene name Protein Wnt
Gene symbol wnt6b
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description Ligand for members of the frizzled family of seven transmembrane receptors.
Sequence
XAVGSPLVMD PNSICRKTKR LAGKQAELCQ TQPEIVNEVA KGAKLGVREC QYQFRFRRWN 60
CTSQNKYFGK ILQQDIRETA FVYAITAAGV THAVTQACSM GELLQCGCEA TRSRGPPPRL 120
ASMGPTEGVK WEWGGCGDDV EFGYEKSKQF MDARRRKGKS DIRTLIDLHN NEAGRLAVKN 180
YMRTECKCHG LSGSCTLRTC WKKMPHFREV GDRLLERFNG ASKVMGGNDG KTLIPVGQNI 240
KPPDKQDLIY SAESPDFCLP NRKTGSLGTR GRTCNSTALD VSGCDLLCCE RGHRDETVVL 300
EENCLCRFHW CCVVQCKKCL VRKELSLCQ 329

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologWNT6505075F1MN70Bos taurusPredictionMore>>
1:1 orthologWNT6A0A452FTD5Capra hircusPredictionMore>>
1:1 orthologWNT67475Q9Y6F9Homo sapiensPublicationMore>>
1:1 orthologWnt622420P22727E14.5Mus musculusPredictionMore>>
1:1 orthologWNT6742467A0A2I3SR43Pan troglodytesPredictionMore>>
1:1 orthologWNT6A0A287BRH3Sus scrofaPredictionMore>>
1:1 orthologWNT6G1TQH3Oryctolagus cuniculusPredictionMore>>
1:1 orthologWnt6316526D4A3W9Rattus norvegicusPredictionMore>>
1:1 orthologwnt6bF1RAB5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005615 extracellular space
GO:0005125 cytokine activity
GO:0005109 frizzled binding
GO:0060070 canonical Wnt signaling pathway
GO:0045165 cell fate commitment
GO:0030182 neuron differentiation

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0217 Developmental protein
KW-0272 Extracellular matrix
KW-0449 Lipoprotein
KW-1185 Reference proteome
KW-0964 Secreted
KW-0732 Signal
KW-0879 Wnt signaling pathway

Interpro

InterPro ID InterPro Term
IPR005817 Wnt
IPR043158 Wnt_C
IPR018161 Wnt_CS

PROSITE

PROSITE ID PROSITE Term
PS00246 WNT1

Pfam

Pfam ID Pfam Term
PF00110 wnt