| Tag | Content |
|---|---|
| Uniprot ID | G1TQH3 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSOCUP00000019268 |
| Ensembl nucleotide ID | ENSOCUG00000024007 |
| Gene name | Protein Wnt |
| Gene symbol | WNT6 |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Ligand for members of the frizzled family of seven transmembrane receptors. |
| Sequence | AVGSPLVMDP TSICRKARRL AGRQAELCQA EPEVVAELAR GARLGVRECQ FQFRFRRWNC 60 SSHSKAFGRI LQQDIRETAF VFAITAAGAS HAVTQACSMG ELLQCGCQAP RGRGPPRPSG 120 LPGTPGPPGP AGPADASAAW EWGGCGDDVD FGDEKSRLFM DAQHKRGRGD IRALVQLHNN 180 EAGRLAVRSH TRTECKCHGL SGSCALRTCW QKLPPFREVG ARLLERFHGA SRVMGTNDGK 240 ALLPAVRTLK PPGRADLLYA ADSPDFCAPN RRTGSPGTRG RACNSSAPDL SGCDLLCCGR 300 GHRQESVQLE ENCLCRFHWC CVVQCHRCRV RKELSLCL 338 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | WNT6 | 505075 | F1MN70 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | WNT6 | A0A452FTD5 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | WNT6 | 7475 | Q9Y6F9 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Wnt6 | 22420 | P22727 | E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | WNT6 | 742467 | A0A2I3SR43 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | WNT6 | A0A287BRH3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | WNT6 | G1TQH3 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Wnt6 | 316526 | D4A3W9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | wnt6b | F1RAB5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0009986 | cell surface |
| GO:0031012 | extracellular matrix |
| GO:0005102 | signaling receptor binding |
| GO:0009798 | axis specification |
| GO:0001658 | branching involved in ureteric bud morphogenesis |
| GO:0060684 | epithelial-mesenchymal cell signaling |
| GO:0072079 | nephron tubule formation |
| GO:0042475 | odontogenesis of dentin-containing tooth |
| GO:0070172 | positive regulation of tooth mineralization |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| GO:0016055 | Wnt signaling pathway |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00246 | WNT1 |
| Pfam ID | Pfam Term |
|---|---|
| PF00110 | wnt |