| Tag | Content |
|---|---|
| Uniprot ID | A0A452G0M2 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000029859 |
| Ensembl nucleotide ID | ENSCHIG00000024787 |
| Gene name | Uncharacterized protein |
| Gene symbol | FRAS1 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | TIVISEECAV NIKRKKFRGI PSQVPACIYF NSTYASSQDA TIWKPDSCQN CRCHGDIVIC 60 KPAVCRNPQC AFEKGEVLQI PANQCCPECV PRMPGSCHHE KKIHGHGTAW ASSSCSMCSC 120 THGEVRCAPR PCPPLMCGYQ ELEFIPEGSC CPVCVGSGKS CSYEGRVFQD GEDWPLSRCA 180 KCVCRNGVAQ CFASQCPPLF CSQDETIVRI PGKCCPQCSS RSCSAAGQVY EHGEQWHENA 240 CTTCTCDQGE VRCHKQPCPP LRCEKGQRRA RRQGQCCEDC VSPAGSCSHR GLVRYQDEMW 300 KASACEFCVC DRGQVTCQTA ECAKVECARG EELIHLEGKC CPECISRNGY CVYKENAEFM 360 SSNASKIKHI PEGEKWEDGP CKVCECRGAQ VTCYEPSCPP CPVATLAQVV EGQCCPECTS 420 VRCHPDCLTC SQSPDHCDLC QDPTKLLRNG QCVHSCGLGF YQAGAFCLAC QPHCSTCTSG 480 LECSSCQPPL LMQEGQCVST CGISFYQDHR SCAACHESCA ACWGPTEKHC LACREPLHVL 540 REGGCESSCG NGFYNKQGTC SACDQSCKSC GPSSPRCLTC VEKTVLHDGK CLSECPGGYY 600 ADATGRCKVC HNSCASCSGP TASHCTACIQ PQALRQGHCL PNCGEGFYPD HGVCKACHSS 660 CLTCVGPAHS HCTQCRKPED GLQFDPLSGA NITLGECLSQ CRAQFYLENT GLCEACHPSC 720 SACAGTSPHN CTACWPSHVL LDGQCLSQCP DGYFNQEGSC TECHPTCRQC HGPLESDCIS 780 CHPHIPLTAG SCRASCKEEQ FLNLVGYCAD CHPLCHHCVA NLRDTGSICL QCQNARNLLL 840 GDRCVPDCPS GYFVEREACK KCHSSCRTCQ GRGPFSCSSC DTGRVLSHLG TCSTTCFPGH 900 YLDDNRVCQP CNMHCGSCDS QASCTSCRDP SKVLLFGDCQ HESCAPQYYL DFSTKTCKEC 960 DWSCNACSGP LRTECLQCMD GYVLQDGACV EQCSASFYRD VDLCKSCESH CLQCQGPHEC 1020 TRCEEPFLLL EAQCVQECGK GFFADHANHK CTACPKGCLQ CSRRDWCHLC DQGFFLKSGL 1080 CLSNCVPGFS SHSSNETCAG KIHTPSLHVN GSLTLAIGSM KPLDFFLLNV QDQGGRVEDL 1140 LFHVVSTPTN GQLVLSRNGK EAQLDKAGHF SWKDVKEKRV RFVHSREKPR KGYFSLKISD 1200 QQFFSEPQLI NIQAFSTQAP YVLRNEVLQI NRGERGTVTT QLLDIRDDDN PQDVLVQVLD 1260 PPLHGQLLQT LQSPAAPIYQ FRLDELSRGL LQYVHDGSDS ASDIIVLQAN DGHSFQNILF 1320 RIRTVPKNDR GLRLVANSMV WVPEGGMLQI TNRILQAEAP GASAAEIIYK ITQDHPQFGD 1380 VVLLVNMPAD SPADGGQHLP DGRTATPTST FTQQDINEGI VWYRHSGVPA QSDSFRFQVS 1440 SATEAHAHLE SRLFNIAILP HTPEAPQHFP GSSLHMTVNG LTVIQPHSLS FVNPERPSGK 1500 IIYNITLPLH PNQGIIEHRD QPHSPIRYFS QEDVNQGNIM YRPPTAAPHL QEIRAFSFAV 1560 SDGEHTSPEM ALTIHLLRTD QHPPVFQVTA PLLEVSPGGS TSIELQLEVR DTKTVPEELL 1620 FELRKPPQHG VLIKYTAGSP GPMATGDTFT YEDVEKNVLQ YLHDGSSAQE DSMEILVTDG 1680 LSATTVDVRV EVSLAEARGP RLAAGASLSI TVASKSTAVI TRSHLAYVDD SSSDPEIWIQ 1740 ITSLPMYGAL LKTSGPEVEE LSEISNFTME DINNKKIRYL AAFETGGHPV TDSFHFSVSD 1800 MDHNRLDNQK FTITITPDKD PPPVIAFADL ITVDEGGRTP LSFHHFFAAA AEDSFQEDAV 1860 IKLSALPQYG CIENTGTGDR FGPGTTSDLE ASFPIQDVLE NYIYYFQSVH ESIEPTYDIF 1920 SFYVSDGNSR SEVHSINITI ERKNDEPPRV TLRPLGVQLS SGVVISNSSL SLQDLDTPDN 1980 ELIFVLTKEP GHGHLLRRQT ASEPLENGRV LAQGSSFTYQ DILAGLVGYM PGGPGVAVDE 2040 FRFSLTDGLH TDTGRMEIYI ELPTSDNPQL AVNRGLQLSA GSVATITEQH LKVTDPDSDD 2100 RQVMYILKED PGVGRLQMVK RDSLEQISTR GPIRSFTQAD LTQGLIEYSH GKGESGGNFA 2160 FKFDVVDGEG NKLIGQSFSI SVSEDKSPPV IITNKGLFLD ENSVKKITTL QLSATDQETG 2220 PAELVYRITR EPQLGHLEHT ASPGIQISSF TQADLTSGNV QYVHSSETEK HSDAFSFTLS 2280 DGVHEVTQTF RITLRPVDDA LPHVQNFGMR VQEGVKKAIT EFELKAVDAD TEAESVTFTV 2340 VQPPRHGIIE RTADGQPFQL TPTFTMEDIY QSRVRYSHDG SNSLRDRFTF TVADGTNPFF 2400 IVEEGGKEII TAAPQQFWVD ILPVDDGTPK IVTNLGLQWL EYMDGKATNL ITKKELLTMD 2460 PDTEDLQLVY EITTGPKHGH VESKLQPGRA VATFTQEDVN LGLIRYVLHE EKIHEMMDSF 2520 QFLVKDSKPN VVNDNIFHIQ WSLISFKYTS YNVSEKAGSV SVTVQRTGNL NQYAIVLCRT 2580 EQGTATSSSR PGQQDYVEYA GQVQFDERED TKSCTIVIND DDVFENIESF TVELSMPAYA 2640 LLGEFTQAKV IINDTEDEPT LEFDKKTYRV NESAGFLFAP IERKGDSSSI VSVICHTVPK 2700 SAMGSSLYAL ESGSDFKSRG MSAESRVIFG PGVTMSTCDV MIIDDSEYEE EEEFEIALTG 2760 ASDNARIGRV ASAKVLIAGP NDASTVSLGN TAFTISEDAG TVKIPVIRHG TDLSTFTSVW 2820 CATRPSDPAS ATPGVDYVPS SRKVEFGPGV TEQYCTLTIL DDTQYPVIEG LETFVVFLSS 2880 PQGAELTKPF QAVIAINDTF QDVPSMQFAK DLLLVKEKEG VLHVPIIRSG DLSYESSVRC 2940 YTQGLSAQVM EDFEERRNAD SSRITFLKGE KMKNCTVYIH DDSMFEPEEQ FRVYLGRPLG 3000 NHWSGARVGK NHMATITIAN DEDAPTIEFE EAAYQVREPS GPDATAILNV KVIRRGDQNR 3060 TSKIRCSTRD GSAQSGVDYY PKSRVLKFSP GVDHIFFKVE ILSNEDREWH ESFSLVLGPD 3120 DPVEAVLGDV TTATVTILDQ EAAGSLILPA PPIVITLADY DHVEEVTKEG VKKSPSPGYP 3180 LVCVTPCDPH FPKYAVMKER CHEAGINQTS VQFSWEVAAP TDGNGARSPF ETITDNTPFT 3240 SVNHMVLDSI YFSRRFHVRC VAKAVDKVGH VGTPLRSNIV TIGTDSAICH TPVVAGTARG 3300 FQAQSFIATL KYLDVKHKEH PNRIHISVQI PHQDGMLPLI STMPLHNLHF LLSESIYRHQ 3360 HVCSNLVTTR DLRGISEAGF LDDRVHDSVA LGPGYDRPFQ FDPRVREPKT IQLYKHLNLK 3420 SCVWTFDAYY DMTELIDVCG GSVTADFQVR DSAQSFLTVH VPLHVSYVYV TAPRGWASLE 3480 HHTEMEFSFF YDTVLWRTGI QTDSVLSARL QIIRIYIRED GRLVIEFKTH AKFRGQFVME 3540 HHTLPDVKSF ILTPDHLGGI EFDLQLLWSA QTFDSPYQLW RATSSYNRKD YSGEYTIYLI 3600 PCTVQPTQPW VDPGEKPLAC TAHAPERFLI PIAFQQTNRP VPVVYSLNTE FQLCNNEKVF 3660 LMDPNTSDMS LAEMDYKGAF SKGQILYGRV LWNPEQNLNS AYKLQLEKVY LCTGKDGYVP 3720 FFDPTGTIYN EGPQYGCIQP NKHLKHRFLL LDRSQPEVTD KYFHDVPFEA HFASELPDFQ 3780 VVSSMPGVDG FTLKVDALYK VEAGHQWYLQ VIYVIGPDTI SGPRVQRSLT APLRRHRRDL 3840 ADPSGWLSLD ESLIYDNEGD QVKNGTNMKS LNLEMQEPIV AASLSQTGAS VGSALAAIML 3900 LLLVSLVACF ITRKCQKQRK KPPTGDILEE YPLNTKVDMP KRGTDRVEKN VDRQYCTVRN 3960 VNVLGEAEGT YVFKGAKVKK LNLEVRVHNN LQDGTEV 3997 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FRAS1 | 478446 | J9P6T8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | FRAS1 | A0A452G0M2 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | FRAS1 | 80144 | Q86XX4 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Fras1 | 231470 | Q80T14 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | FRAS1 | 461226 | H2R4C8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Fras1 | F1M3H3 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | fras1 | 563428 | F1Q633 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005604 | basement membrane |
| GO:0016021 | integral component of membrane |
| GO:0007154 | cell communication |
| GO:0030326 | embryonic limb morphogenesis |
| GO:0003338 | metanephros morphogenesis |
| GO:0002009 | morphogenesis of an epithelium |
| GO:0015031 | protein transport |
| GO:0060021 | roof of mouth development |
| GO:0043588 | skin development |