| Tag | Content |
|---|---|
| Uniprot ID | F1M3H3 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000002814 |
| Ensembl nucleotide ID | ENSRNOG00000002053 |
| Gene name | Fraser extracellular matrix complex subunit 1 |
| Gene symbol | Fras1 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | HGTEWASGPC TLCSCTYGEV RCSHQQCTPL SCGPQELEFL AEGHCCPICV GTGKPCSDDG 60 HVFQDGEDWP LSHCAKCVCR NGLTQCFTAQ CQPLFCNQDE IVVRVPGKCC SQCSSRSCST 120 AGQVYEHGEQ WKEDACTLCM CDQGQVRCHK QACPPLRCAK GQSKARHHGQ CCEECVSPVR 180 SCSSGGVLRY QDEMWKGSAC EFCVCDQGQV TCQTGECAKV ACAPGEELVH LEGKCCPECI 240 SRNDYCVYEE KAEIMSSNSS EIKHVPEGKK WEEGPCKLCE CREAQVTCYE PSCPPCPVAT 300 LAMAVKGQCC PDCTPVHCHP DCLTCSHSPE HCDLCQDPTK LLQNGRCVPS CGLGFYQAGS 360 LCLACQPQCS TCTSSLECSS CLPPLLMQQG QCVSTCGDGF YQDHHSCAVC HESCAGCWGP 420 TEKHCVACRD PLLVLRDGSC ENTCGNGFYN RQGTCVACDQ SCKSCGPSSP RCLTCAEKTV 480 LYDGTCISEC PRGYYADATG RCKVCHVSCA SCSGPAAAHC TACVHPQVLR QGHCLPSCGG 540 GFYPDHGICG ACHGSCHTCV GPEPTHCTQC KKPEAGLQVE QHSGENVPYG KCVSQCGAHF 600 YLESTGLCEA CHPSCLLCEG KSPRNCTGCG PAHVLLAGRC LSQCPETHFN QEGTCTECHP 660 SCRQCHGPLE SDCVSCHPHL TLSSGRCKAS CKDEQFLNLV GYCADCHPLC QHCVANLQDT 720 GSVCLKCQHA RHLLLGDHCV PDCPPGHYKE RGTCKRCHPS CRSCQNGGPF SCSSCNTGLV 780 LTHIGACSST CFPGHYLDDN QACQPCNRHC RSCDSQGSCT SCRDPSKVLL FGECQYESCA 840 PQYYLDISTK TCKECDWSCN ACTGPLRTDC LQCMDGYVLQ DGVCVEQCSP QHYRDSGSCK 900 RCDSHCLQCQ GPHECTRCEG PFLLFRAQCV QECAKGYFAD HAEHKCTACP QGCLQCSHKD 960 RCHLCDHGFF LKSGFCMPTC VPGFSGHSSN ETCTDKVYTP SLHVNGSLTL GIGSMKPLDF 1020 SLLNIQHQDG RVEDLLFHIV STPTNGQLLL SRNGKEVQLE KAGHFSWKDV NGKKVRFVHS 1080 KEKLRKGYFS LKISDQQFFS EPQLINIQAF STQAPYVLRN EVLHISKGER AAITTQLLDI 1140 RDDDNPQDVV LNVLDPPRHG QLLRTPPAPA ASVYQFHVDE LSRGLLLYAH DGSDSTSDII 1200 VFQANDGHSF QNILFREVVL LMNLPADSPA GPAEEGHHLP DGRMTTPVST FSQQDIDDGI 1260 VWYRHSGATA QSDSFHFQVS TATNAQEHPQ SHMFNIAILP QALEAPKLSL GTSLHMTARE 1320 DGLSVIHPQS LSFGKAESPS GKIIYNITVP LHPNQGVIEH RGRPNSPIRY FTQEEINQGQ 1380 IMYRPPAAPP HLQEFMAFSF AGLPESVRFY FTVSDGQHTS PEMALTIHLL HSDRQPPAFQ 1440 IKAPLLEVSP GGRTPLGLQL VVRDAEVVPE ELFFQLQKPP QHGMLMKYTA KSSVTMSAGD 1500 TFTYDEVERN VLQYVHDGSP AWEDNMEISV TDGLTVTTSE VKVEVSPSEN REPRLAPGSS 1560 LSMTVASQHT AIITRSHLAY VDDSSPDSEI WIQLSSLPLY GVLLKTSGPD MEELSGDSNF 1620 TMEDINSKNI RYSAVFETEG QSVTDGFHFS VSDMDNNRVD NQVFTITVTP AENPPHIIAF 1680 ADLITVDEGG RAPLSLHHFF ATEDQDNLQG DAVIKLSALP KYGCIENTGT GDRFGPGANS 1740 ELEASFPIQD VLENYIYYFQ SVHESIEPTH DVFSFYVSDG SGRSEIHSIN ITIERKNDEP 1800 PRMTLRPLGV RLSSGVAISN SSLSLQDLDT PNNELIFVLM KKPDHGYLLL RPTASDPLEN 1860 GTVLDQGSSF TYQDILAGLV GYLPGDIYMA VDEFRFSLTD GLHVDTGRME IYIELPTSNI 1920 PHLAINRGLQ LSAGSVARIT EQHLRATDTD SEAGQLVYIV KEDPGAGHLQ MTKADKLEQI 1980 SVRGPIRSFT QADVSQGQIE YSHGPGEAGG SFAFKFDVVN GEGNKLADQS FSINVLEDKS 2040 PPVIITNKGL VLDENSVEKI TTAQLLATDQ DSKPTELIYR ITSQPQLGHL EHVASPGIQI 2100 SSFTQADLTS RNVQYVHSSG TGKLSDAFSF VLSDGLHEVT QTFSITIHPV DDSLPLVQNR 2160 GMRVQEGVRK TITEFELKAV DVDTEAESIT FTIVQPPRHG TIERTARGQR YQLTSSFTME 2220 DIYQNRVSYS HDGSNSLKDR FTFTVSDGTN PFFIIEEGGE EIMTAAPQQF LVDILPVDDG 2280 TPRIVTNLGL QWLEYMDGKA TNLITKKELL TVDPDTEDSQ LTYEVTTGPM HGYVENKLQP 2340 GRVAATFTQE HVNLGLIRYV LYEEKIQKMM DSFQFLVKDS KPNVVSDNIF YIHWSLISFK 2400 YTSYNVSEKA GSVSVMVQRT GNLNQYAIVL CRTEQGTASS SSRVSSHPGQ QDYVEYAGQV 2460 QFDEREDTKS CTIVINDDDV FENIESFTVE LSMPAYALLG EFTQAKVIIN DTEDEPTLEF 2520 DKKTYRVNES AGFLFAPIKR QGDPSSAVSA ICYTVPKSAM GSSLYALESG SDFKSRGRSV 2580 ESRVLLGPGV TTSTCDVMVI DDSEYEEEEE FEIALADASN NARIGRLAVA KVLISGPNDA 2640 STVSLGNTAF TISEDAGTVK VPVIRHGTDL STFTSVWCAT RPSDPASATP GVDYVPSSPK 2700 KVEFGPGVHR AYCTLTILDD TQYPVIEGLE TFVVFLSSAQ GAELTKPSQA VIAINDTFQD 2760 VPSMQFSKDL LLVKEKEGVL HIPIIRSGDL SYESSVRCYT QSHSAQVMED FEERRNADSS 2820 RITFLKGEKA KNCTVYIHDD SMFEPEEQFR VYLGHPLGNH WSGARIGKNS MATVTISNDE 2880 DAPTIEFEEA AHQVREPAGP DATAVLSVKV IRRGDQNRTS KIRCSTRDGS AQSGVDYYPK 2940 SRVLKFSPGV DHIFFKVEIL SNEDREWHES FSLVLGPDDP VEAVLGDVTT ATVTILDQEA 3000 AGSLILPAPP IVVTLADYDH VEELSKEGVK KAPSPGYPLV CVTPCDPHYP RYAVMKERCS 3060 EAGINQTSVQ FSWEVAAPTD GNGARSPFET ITDSTPFTSV NHKVLDSIYF SRRFHVRCVA 3120 KAVDKVGHVG TPLRSNVVTI GTDSAICQPP VVAGTARGFQ AQSFIATLKY LDVKHKEHPN 3180 RIHISVQIPH QDGMLPPNLR PTCPYTNLHF LLSESIYRQQ HVCSNLVTAR DLRGLSEAGF 3240 LDDAGLHSTA LGPGYDRPFQ FDPSVREPKT IQLYRHLNLK SCVWTFDAYY DMTELIDVCG 3300 GSVTADFQVR DSAQSFLTVH VPLYVSYIYV TAPRGWASLE HHTEMEFSFF YDTVLWRTGI 3360 QTDSVLSARL QILRIYIRED GRLVIEFKTH AKFRGQFVIE HHTLPDVKSF ILTPDHLGGI 3420 QFDLQLLWSA QTFDSPHQLW RATSSYNRKD YSGEYTIYLI PCTVQPTQPW VDPGEKSLAC 3480 TAHAPERFLI PIAFQQTNRP VPVVYSLNTE FQLCNNEKVF LMDPNTSDMS LAEMDYKGAF 3540 SKGQILYGRV LWNPEQNLHS AYKLQLEKVY LCTGKDGYVP FFDPTGTIYN EGPQYGCIQP 3600 NKHLKHRFLL LDRSQPEVTD KYFHDVPFEA HFASELPDFQ VVSSMPGVDG FTLKVDALYK 3660 VEAGHQWYLQ VIYIISPDSI SRPRVQRSLT ASLRRHQRDL VDPSGWLSLD DSLIYDNEGD 3720 QVKNGTNMKS LNLELQEPVI AASLSQSGAS IGSALAALML LLLLFLVACF ITRKCQKQKK 3780 KQPPEDTLEE YPLNTKVDVA KKNTDKGEKN ANRQYCTVRN VNILSDSEGY YTFKGAKVKK 3840 LNLEVRVHNN LQDGTEV 3857 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FRAS1 | 478446 | J9P6T8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | FRAS1 | A0A452G0M2 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | FRAS1 | 80144 | Q86XX4 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Fras1 | 231470 | Q80T14 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | FRAS1 | 461226 | H2R4C8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Fras1 | F1M3H3 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | fras1 | 563428 | F1Q633 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005604 | basement membrane |
| GO:0016021 | integral component of membrane |
| GO:0007154 | cell communication |
| GO:0030326 | embryonic limb morphogenesis |
| GO:0003338 | metanephros morphogenesis |
| GO:0002009 | morphogenesis of an epithelium |
| GO:0015031 | protein transport |
| GO:0060021 | roof of mouth development |
| GO:0043588 | skin development |