| Tag | Content |
|---|---|
| Uniprot ID | A0A452GBK2 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000033827 |
| Ensembl nucleotide ID | ENSCHIG00000027214 |
| Gene name | G_PROTEIN_RECEP_F1_2 domain-containing protein |
| Gene symbol | LGR4 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPGPLGLLCF FALGLRGSAE PSGAAPPLCA APCSCDGDRR VDCSGKGLTA VPEGLSAFTQ 60 LDISMNNITQ LPEDAFKNFP FLEELRLAGN DLSFIHPKAL SGLKELKVLT LQNNQLKTVP 120 SEAIRGLSSL QSLRLDANHI TSVPEDSFEG LTQLRHLWLD DNSLTEVPVH PLSNLPTLQA 180 LTLALNKISS IPDFAFTNLS SLVVLHLHNN KIKSLGQHCF DGLDNLETLD LNYNNLGEFP 240 QAIKALPSLK ELLFHSNSIS VIPDGAFDGN PLLKTIHLYD NPLSFVGNSA FHNLSELHSL 300 TAFCLPCQLE SFLRQTMFLH RTLTGTKISS IPSNLCQEQK RLRTLDLSYN SIKDLPSFNG 360 CHALEEISLQ RNQIHKIKED TFQEANKIVV KLDVSFNELT SFPTEGLNGL NQLKLVGNFK 420 LKEALAAKDF VNLRCVFLFC ESFGRPSDYR VSCLSDVAGV TSSAENEEHS QIIIHCTPST 480 GAFKPCEYLL GSWMIRLTVW FIFLVALFFN LLVILTTFAS CASVPSSKLF IGLISVSNLF 540 MGAYTGILTF LDAVSWGRFA EFGIWWEIGS GCKIAGFLAV FSSESAIFLL MLAAIERSLS 600 AKDMMKNGKS SHLKQFRIAA LLAFLGAAVA GCFPLFHRGE YSASPLCLPF PTGETPSLGF 660 TVTLVLLNSL AFLLMAIIYT KLYCNLEKED LSENSHSSMI KHVAWLIFTN CIFFCPVAFF 720 SFAPLITAIS ISPEIMKSVT LIFFPLPACL NPVLYVFFNP KFKEDWKLLK RHVTKKSGSA 780 SVSISSQAGC VEQDFYYDCG MYSHLQGNLT VCDCCEAFLL TKPVSCKHLI KSHSCPALTV 840 GSCQRPDGYW SDCGTQSAHS DYADEEDSFV SDSSDQVQAC GRACFYQSRG FPLVRYAYNL 900 PRVKD 905 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | LGR4 | A0A452GBK2 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | LGR4 | 55366 | Q9BXB1 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Lgr4 | 107515 | A2ARI4 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | LGR4 | H2R5I5 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | LGR4 | 100518646 | F1SGM5 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | LGR4 | 100356429 | G1SL01 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Lgr4 | 286994 | Q9Z2H4 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | lgr4 | 558825 | E7FE13 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0004930 | G protein-coupled receptor activity |
| GO:0016500 | protein-hormone receptor activity |