| Tag | Content |
|---|---|
| Uniprot ID | H2R5I5 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000048194 |
| Ensembl nucleotide ID | ENSPTRG00000028697 |
| Gene name | Leucine rich repeat containing G protein-coupled receptor 4 |
| Gene symbol | LGR4 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPGPLGLLCF LALGLLGSAG PSGAAPPLCA APCSCDGDRR VDCSGKGLTA VPEGLSAFTQ 60 ALQLAGNDLS FIHPKALSGL KELKVLTLQN NQLKTVPSEA IRGLSALQSL RLDANHITSV 120 PEDSFEGLVQ LRHLWLDDNS LTEVPVHPLS NLPTLQALTL ALNKISSIPD FAFTNLSSLV 180 VLHLHNNKIK SLSQHCFDGL DNLETLDLNY NNLGEFPQAI KALPSLKELG FHSNSISVIP 240 DGAFDGNPLL RTIHLYDNPL SFVGNSAFHN LSDLHSLVIR GASMVQQFPN LTGTVHLESL 300 TLTGTKISSI PNNLCQEQKM LRTLDLSYNN IRDLPSFNGC HALEEISLQR NQIYQIKEGT 360 FQGLISLRIL DLSRNLIHEI HSRAFATLGP ITNLDVSFNE LTSFPTEGLN GLNQLKLVGN 420 FKLKEALAAK DFVNLRSLSV PYAYQCCAFW GCDSYANLNT EDNSLQDHSV AQEKGTADAA 480 NVTSTVENEE HSQIIIHCTP STGAFKPCEY LLGSWMIRLT VWFIFLVALF FNLLVILTTF 540 ASCTSLPSSK LFIGLISVSN LFMGIYTGIL TFLDAVSWGR FAEFGIWWET GSGCKVAGFL 600 AVFSSESAIF LLMLATVERS LSAKDIMKNG KSNHLKQFRV AALLAFLGAT VAGCFPLFHR 660 GEYSASPLCL PFPTGETPSL GFTVTLVLLN SLAFLLMAII YTKLYCNLEK EDLSENSQSS 720 MIKHVAWLIF TNCIFFCPVA FFSFAPLITA ISISPEIMKS VTLIFFPLPA CLNPVLYVFF 780 NPKFKEDWKL LKRRVTKKSG SVSVSISSQG GCLEQDFYYD CGMYSHLQGN LTVCDCCESF 840 LLTKPVSCKH LIKSHSCPAL AVASCQRPEG YWSDCGTQSA HSDYADEEDS FVSDSSDQVQ 900 ACGRACFYQS RGFPLVRYAY NLPRVKD 927 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | LGR4 | A0A452GBK2 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | LGR4 | 55366 | Q9BXB1 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Lgr4 | 107515 | A2ARI4 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | LGR4 | H2R5I5 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | LGR4 | 100518646 | F1SGM5 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | LGR4 | 100356429 | G1SL01 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Lgr4 | 286994 | Q9Z2H4 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | lgr4 | 558825 | E7FE13 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0004930 | G protein-coupled receptor activity |
| GO:0016500 | protein-hormone receptor activity |