| Tag | Content |
|---|---|
| Uniprot ID | A0A4D6PF96 |
| Entrez ID | 477488 |
| Genbank protein ID | QCF24315.1 |
| Genbank nucleotide ID | XM_005636251.1 |
| Ensembl protein ID | |
| Ensembl nucleotide ID | |
| Gene name | Tyrosine-protein phosphatase non-receptor type |
| Gene symbol | PTPN11 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTSRRWFHPN ITGVEAENLL LTRGVDGSFL ARPSKSNPGD FTLSVRRNGA VTHIKIQNTG 60 DYYDLYGGEK FATLAELVQY YMEHHGQLKE KNGDVIELKY PLNCADPTSE RWFHGHLSGK 120 EAEKLLTEKG KHGSFLVRES QSHPGDFVLS VRTGDDKGES NDGKSKVTHV MIRCQELKYD 180 VGGGERFDSL TDLVEHYKKN PMVETLGTVL QLKQPLNTTR INAAEIESRV RELSKLAETT 240 DKVKQGFWEE FETLQQQECK LLYSRKEGQR QENKNKNRYK NILPFDHTRV VLHDGDPNEP 300 VSDYINANII MPEFETKCNN SKPKKSYIAT QGCLQNTVND FWRMVFQENS RVIVMTTKEV 360 ERGKSKCVKY WPDEYALKEY GVMRVRNVKE SAAHDYTLRE LKLSKVGQGN TERTVWQYHF 420 RTWPDHGVPS DPGGVLDFLE EVHHKQESIT DAGPVVVHCS AGIGRTGTFI VIDILIDIIR 480 EKGVDCDIDV PKTIQMVRSQ RSGMVQTEAQ YRFIYMAVQH YIETLQRRIE EEQKSKRKGH 540 EYTNIKYSLT DQTSGDQSPL PPCTPTPSCA EMREDNARVY ENVGLMQQQK SFR 593 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PTPN11 | 477488 | A0A4D6PF96 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | PTPN11 | 102177271 | A0A452F960 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PTPN11 | 5781 | Q06124 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ptpn11 | 19247 | P35235 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PTPN11 | I3L916 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Ptpn11 | 25622 | P41499 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ptpn11a | F1QZU5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0004725 | protein tyrosine phosphatase activity |