Gene: QSOX1

Basic information

Tag Content
Uniprot ID A0A5F4CZM1
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCAFP00000059803
Ensembl nucleotide ID ENSCAFG00000012717
Gene name Sulfhydryl oxidase
Gene symbol QSOX1
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
AAPRSALYSS SHLALLQADT VRGALLGSRS AWAVEFFASW CGHCIAFAPT WKALAQDVKD 60
WRPALNLAAL DCADETNNAV CRDFNIPGFP TVRFFKAFSK NGSGTTLPVA GADVETLRKR 120
LIDALESHSD TWPPACPPLE PARLEEIDGF FARNDDEYLA LIFEKEGSYL GREVALDLSQ 180
HQGIAVRRVL NTEGDVVSKF GVTDFPSCYL LFRNGSTSRV HVLQESRPFY TAYLKKFSKL 240
IREAVPTKVV PTTVHTIAPT VWKVVDRSKI YMADLESALH YILRVEVGKF SVLEGQRLVA 300
LKKFMAVLAQ HFPGQPLVQN FLHSVNDWLK RQQRKKIPYS FFKAALDNRK EGTMIAKKVH 360
WVGCQGSEPH FRGFPCSLWI LFHFLTVQAA RHNLDHSQET AEAQEVLQAI RSYVRFFFGC 420
RDCANHFEQM AAASMNRVDS LNSAVLWLWS SHNKVNARLA GAASEDPHFP KVQWPPRGLC 480
SACHNDLRGS PVWDLDNTLR FLKTHFSPSN VVLDMPSAVP GPQMGALRMA AGNVTLGPKK 540
AGIAVGPGTK SPGTTVPEVP TERLSATYPQ DMLLGLSVTP AEPDRGSREH RAELQMDKLE 600
QPKGQQHLTK RDTGTVLLAE FLAEKNLPRN PSELRRVGRS SKQLASIPEG EPEAGPMGGR 660
DQWLQVLEGN FSHLDISLCV GLYSLSFMGL LAIYTYFRAR MRALKGHPGH PAA 713

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologQSOX1A0A5F4CZM1Canis lupus familiarisPredictionMore>>
1:1 orthologQSOX1A0A452FQZ4Capra hircusPredictionMore>>
1:1 orthologQSOX15768O00391Homo sapiensPredictionMore>>
1:1 orthologQsox1104009Q8BND5CPOMus musculusPublicationMore>>
1:1 orthologQSOX1457558K7DF20Pan troglodytesPredictionMore>>
1:1 orthologQSOX1F1S682Sus scrofaPredictionMore>>
1:1 orthologQSOX1100350171G1SND0Oryctolagus cuniculusPredictionMore>>
1:1 orthologQsox184491Q6IUU3Rattus norvegicusPredictionMore>>
1:1 orthologqsox1100004382B0UXN0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005623 cell
GO:0016021 integral component of membrane
GO:0016971 flavin-linked sulfhydryl oxidase activity
GO:0045454 cell redox homeostasis

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0274 FAD
KW-0285 Flavoprotein
KW-0472 Membrane
KW-0560 Oxidoreductase
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR036774 ERV/ALR_sulphydryl_oxid_sf
IPR017905 ERV/ALR_sulphydryl_oxidase
IPR040986 QSOX_FAD-bd_dom
IPR042568 QSOX_FAD-bd_sf
IPR041269 QSOX_Trx1
IPR039798 Sulfhydryl_oxidase
IPR036249 Thioredoxin-like_sf
IPR013766 Thioredoxin_domain

PROSITE

PROSITE ID PROSITE Term
PS51324 ERV_ALR
PS51352 THIOREDOXIN_2

Pfam

Pfam ID Pfam Term
PF04777 Evr1_Alr
PF18371 FAD_SOX
PF18108 QSOX_Trx1
PF00085 Thioredoxin