Gene: QSOX1

Basic information

Tag Content
Uniprot ID F1S682
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000016471
Ensembl nucleotide ID ENSSSCG00000015535
Gene name Sulfhydryl oxidase
Gene symbol QSOX1
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MGSCGRGSGP PLSLLLLAVL LAVPGAGAAP RSALYSSSDP LTLLQADTVR GAVLGSRSAW 60
AVEFFASWCG HCIAFAPTWK ALANDVKDWR PALNLAALDC AEETNNAVCR EFDIPGFPTV 120
RFFKAFSRTG SGATLPVAGA DVQTLRERLI DALETHSDTW PPACPPLEPA RLEEITGFFA 180
RNSEEYLALI FEKEGSYLGR EVALDLSQRQ GIAVRRVLNT ERNVVSKFSV TDFPSCYLLF 240
RNGSFSRVPV LMESRSFYTA YLQRLSGVIR KPVPTTTVPT TTRTVAPTVW KVADPSKIYM 300
ADLESALHYI LRVEVGKFSV LEGQRLVALK KFVAVLAQYF PGQPLVQNFL HSVNDWLKKQ 360
PRKKIPYGFF KTVLDNRKEG AVIADKVNWV GCQGSEPHFR GFPCSLWILF HFLTVQASRQ 420
SVDPSQETAK AQEVLQAIRG YVRFFFGCRD CAAHFEKMAS GSMHRVGSPN SAVLWLWSSH 480
NKVNARLAGA PSEDPQFPKV QWPPRELCPA CHNELRGAPV WDLGNSLNFL KTHFSPSNIV 540
LDLPSARLGP QRGAQRMAVN PEQVELELAA GNFTLGPPEK VEIMLGPGTE SPGATIPDVP 600
AEEPGASHPQ ERQDPPEYIA ELQRDELEQP VGQQRLTRRD TGAVLLAEFL AEKTLPRGPS 660
ELRRVGRSSK QLASIPDGEP KPGAMPGRGQ WLQVLEGNFS HLDISLCVGL YSLSFMGLLA 720
AYTYFRARIR ALKGHASHPA A 741

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologQSOX1A0A5F4CZM1Canis lupus familiarisPredictionMore>>
1:1 orthologQSOX1A0A452FQZ4Capra hircusPredictionMore>>
1:1 orthologQSOX15768O00391Homo sapiensPredictionMore>>
1:1 orthologQsox1104009Q8BND5CPOMus musculusPublicationMore>>
1:1 orthologQSOX1457558K7DF20Pan troglodytesPredictionMore>>
1:1 orthologQSOX1F1S682Sus scrofaPredictionMore>>
1:1 orthologQSOX1100350171G1SND0Oryctolagus cuniculusPredictionMore>>
1:1 orthologQsox184491Q6IUU3Rattus norvegicusPredictionMore>>
1:1 orthologqsox1100004382B0UXN0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005623 cell
GO:0070062 extracellular exosome
GO:0005615 extracellular space
GO:0030173 integral component of Golgi membrane
GO:0045171 intercellular bridge
GO:0071949 FAD binding
GO:0016971 flavin-linked sulfhydryl oxidase activity
GO:0003756 protein disulfide isomerase activity
GO:0045454 cell redox homeostasis
GO:0085029 extracellular matrix assembly
GO:0016242 negative regulation of macroautophagy
GO:0006457 protein folding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0274 FAD
KW-0285 Flavoprotein
KW-0472 Membrane
KW-0560 Oxidoreductase
KW-1267 Proteomics identification
KW-1185 Reference proteome
KW-0732 Signal
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR036774 ERV/ALR_sulphydryl_oxid_sf
IPR017905 ERV/ALR_sulphydryl_oxidase
IPR040986 QSOX_FAD-bd_dom
IPR042568 QSOX_FAD-bd_sf
IPR041269 QSOX_Trx1
IPR039798 Sulfhydryl_oxidase
IPR036249 Thioredoxin-like_sf
IPR013766 Thioredoxin_domain

PROSITE

PROSITE ID PROSITE Term
PS51324 ERV_ALR
PS51352 THIOREDOXIN_2

Pfam

Pfam ID Pfam Term
PF04777 Evr1_Alr
PF18371 FAD_SOX
PF18108 QSOX_Trx1
PF00085 Thioredoxin