Gene: QSOX1

Basic information

Tag Content
Uniprot ID K7DF20; A0A2J8N6Q8;
Entrez ID 457558
Genbank protein ID JAA32302.1
Genbank nucleotide ID XM_016933529.1
Ensembl protein ID ENSPTRP00000078705
Ensembl nucleotide ID ENSPTRG00000001739
Gene name Sulfhydryl oxidase
Gene symbol QSOX1
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MGRCNRGSGP PPSLLQLLLL WLLAVPGANA APRSALYSPS DPLTLLQADT VRGAVLGSRS 60
AWAVEFFASW CGHCIAFAPT WKALAEDVKA WRPALYLAAL DCAEETNSAV CRDFNIPGFP 120
TVRFFKAFTK NGSGAVFPVA GADVQTLRER LIDALESHHD TWPPACPPLE PAKLEEIDGF 180
FVRNNKEYLA LIFEKGGSYL GREVALDLSQ HKGVAVRRVL NTEANVVRKF GVTDFPSCYL 240
LFRNGSVSRV PVLMESRSFY TAYLQRLSGL TREAAQTTVA PTTANKIAPT VWKFADRSKI 300
YMADLESALH YILRIEVGRF PVLEGQRLVA LKKFVAVLAK YFPGRPLVQN FLHSVNEWLK 360
RQKRNKIPYS FFKTALDNRK EGAVLAKKVN WIGCQGSEPH FRGFPCSLWV LFHFLTVQAA 420
RQNVDHSQEA AKAKEVLPAI RGYVHYFFGC RDCASHFEQM AAASMHRVGS PNAAVLWLWS 480
SHNRVNARLA GAPSEDPQFP KVQWPPRELC SACHNERLDV PVWDVEATLN FLKAHFSPSN 540
IILDFPAAGS AARRDVQNVA AAPELAMGAL ELESRNSTLD PGKPEMMKSP TNTTPDVPAE 600
GPELI 605

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologQSOX1A0A5F4CZM1Canis lupus familiarisPredictionMore>>
1:1 orthologQSOX1A0A452FQZ4Capra hircusPredictionMore>>
1:1 orthologQSOX15768O00391Homo sapiensPredictionMore>>
1:1 orthologQsox1104009Q8BND5CPOMus musculusPublicationMore>>
1:1 orthologQSOX1457558K7DF20Pan troglodytesPredictionMore>>
1:1 orthologQSOX1F1S682Sus scrofaPredictionMore>>
1:1 orthologQSOX1100350171G1SND0Oryctolagus cuniculusPredictionMore>>
1:1 orthologQsox184491Q6IUU3Rattus norvegicusPredictionMore>>
1:1 orthologqsox1100004382B0UXN0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005623 cell
GO:0016971 flavin-linked sulfhydryl oxidase activity
GO:0045454 cell redox homeostasis

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0274 FAD
KW-0285 Flavoprotein
KW-0560 Oxidoreductase
KW-1185 Reference proteome
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR036774 ERV/ALR_sulphydryl_oxid_sf
IPR017905 ERV/ALR_sulphydryl_oxidase
IPR040986 QSOX_FAD-bd_dom
IPR042568 QSOX_FAD-bd_sf
IPR041269 QSOX_Trx1
IPR039798 Sulfhydryl_oxidase
IPR036249 Thioredoxin-like_sf
IPR013766 Thioredoxin_domain

PROSITE

PROSITE ID PROSITE Term
PS51324 ERV_ALR
PS51352 THIOREDOXIN_2

Pfam

Pfam ID Pfam Term
PF04777 Evr1_Alr
PF18371 FAD_SOX
PF18108 QSOX_Trx1
PF00085 Thioredoxin