| Tag | Content |
|---|---|
| Uniprot ID | B0S8K0 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000076101 |
| Ensembl nucleotide ID | ENSDARG00000058733 |
| Gene name | Hedgehog protein |
| Gene symbol | ihha |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Intercellular signal essential for a variety of patterning events during development. |
| Sequence | MRLPVVFGLL VGCALIFAPV NEGCGPGRGH GKRRPPKKLT PLNYKQFSPN VAEKTLGASG 60 RIEGKITRNS ERFKELTPNY NPDIIFKDEE NTGADRLMTQ RCKDKLNSLA ISVMNMWPGV 120 KLRVTEGWDE DGNHFEDSLH YEGRAVDITT SDRDRNKYGM LARLAVEAGF DWVYYESKAH 180 IHCSVKSEHS VAAKTGGCFP ASALVTVEDG SLKTLDSLQP GEKVLASSES DGSGTLVYSE 240 VIAFLDRDPS ARKQFFTIET DSGAKLSLTA AHLLFVSEGN CSGSAANAEL RSVFASDVLP 300 GQCVVSTQAA GRHGRLSRVS RIQMQEDRGV FAPLTSHGTV VVNGIVSSCY AAVDQHWLAH 360 WAFGPLRVLY NWGGPVGHQV TGIHWYSSLL HWIGTQVLDP AHFHPWSMMD NDR 413 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | IHH | 102179616 | A0A452EW38 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | IHH | 3549 | Q14623 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ihh | 16147 | P97812 | CLP | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | IHH | 470652 | H2QJG1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | IHH | 100008942 | G1U6S4 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Ihh | 84399 | F1LP42 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ihha | B0S8K0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0005886 | plasma membrane |
| GO:0005509 | calcium ion binding |
| GO:0005113 | patched binding |
| GO:0008233 | peptidase activity |
| GO:0001708 | cell fate specification |
| GO:0007267 | cell-cell signaling |
| GO:0048484 | enteric nervous system development |
| GO:0016539 | intein-mediated protein splicing |
| GO:0001957 | intramembranous ossification |
| GO:0001649 | osteoblast differentiation |
| GO:0016540 | protein autoprocessing |
| GO:0010468 | regulation of gene expression |
| GO:0007224 | smoothened signaling pathway |
| GO:0048794 | swim bladder development |
| GO:0048795 | swim bladder morphogenesis |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50817 | INTEIN_N_TER |