| Tag | Content |
|---|---|
| Uniprot ID | B3DI86 |
| Entrez ID | |
| Genbank protein ID | AAI63036.1; AAI63048.1; |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000013686 |
| Ensembl nucleotide ID | ENSDARG00000013409 |
| Gene name | Bmp2a protein |
| Gene symbol | bmp2a |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MVSSTAALMV LMVTQVFFAG SSGLVPQVGR SSLSPDVLHA FELRLLSMFG LQHRPTPSSS 60 AVVPQYMLDL YSAHSVNAEQ VSRPRAHLGK GSERSASRAN TIRSFHHDES TEDLSSSSVR 120 TTQRFLFNLT SIPDEELVTS AELRVFREQI VSSLNNASAG FHRINVHEII RPSGSLQEPI 180 TRLLDTRLVQ HSLSKWESFD VTPAVLKWTT DGHPNHGILV EISHPDQDSR KHVRVSRSLH 240 NNEDTWSQMR PLLVTYSHDG KGNVLHSREK RQARNNKQRK KHKANCRRHS LYVDFSDVGW 300 NDWIVAPPGY HAFYCQGECP FPLADHLNST NHAIVQTLVN SVNSNIPRAC CVPTDLSPVS 360 LLYLDEYERV ILKNYQDMVV EGCGCR 386 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BMP2 | 615037 | A5PJI9 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | BMP2 | 477162 | J9P401 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | BMP2 | A0A452EEC2 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | BMP2 | 650 | P12643 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Bmp2 | 12156 | P21274 | CPO | E12.5, E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | BMP2 | 458090 | H2QJY1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | BMP2 | 100157103 | A0A286ZZE2 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | BMP2 | G1T1R1 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Bmp2 | G3V8W4 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | bmp2a | B3DI86 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0070700 | BMP receptor binding |
| GO:0005125 | cytokine activity |
| GO:0008083 | growth factor activity |
| GO:0030509 | BMP signaling pathway |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0030513 | positive regulation of BMP signaling pathway |
| GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation |
| GO:0060395 | SMAD protein signal transduction |