CleftGeneDB-Search

Gene: BMP2

Basic information

Tag	Content
Uniprot ID	G1T1R1
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID	ENSOCUP00000010036
Ensembl nucleotide ID	ENSOCUG00000011674
Gene name	Bone morphogenetic protein 2
Gene symbol	BMP2
Organism	Oryctolagus cuniculus
NCBI taxa ID	9986
Cleft type
Developmental stage
Data sources	Homology search
Reference
Functional description
Sequence	GKTTRRFFFN LTSIPPEEFI TSAELQVFRE QMQEALGDDS GFHHRINIYE IIKPATANSK 60 FPATRLLDTR LVNQNTSRWE SFDVTPAVMR WTAQGHANHG FVVEVTHLEE KQGVSKRHVR 120 ISRSLHPDEH SWSQIRPLLV TFGHDGKGHP LHRREKRQAK HKQRKRLKSS CKRHPLYVDF 180 SDVGWNDWIV APPGYHAFYC HGECPFPLAD HLNSTNHAIV QTLVNSVNSK IPKACCVPTE 240 LSAISMLYLD ENEKVVLKNY QDMVVEGCGC R 271

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

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Relation	Gene symbol	Entrez ID	UniProt ID	Cleft type	Developmental stage	Species	Evidence	Details
1:1 ortholog	Bmp2	12156	P21274	CPO	E12.5, E13.5, E14.5	Mus musculus	Publication	More>>
1:1 ortholog	BMP2	615037	A5PJI9			Bos taurus	Prediction	More>>
1:1 ortholog	BMP2	477162	J9P401			Canis lupus familiaris	Prediction	More>>
1:1 ortholog	BMP2		A0A452EEC2			Capra hircus	Prediction	More>>
1:1 ortholog	BMP2	650	P12643			Homo sapiens	Prediction	More>>
1:1 ortholog	BMP2	458090	H2QJY1			Pan troglodytes	Prediction	More>>
1:1 ortholog	BMP2	100157103	A0A286ZZE2			Sus scrofa	Prediction	More>>
1:1 ortholog	BMP2		G1T1R1			Oryctolagus cuniculus	Prediction	More>>
1:1 ortholog	Bmp2		G3V8W4			Rattus norvegicus	Prediction	More>>
1:1 ortholog	bmp2a		B3DI86			Danio rerio	Prediction	More>>

Showing 1 to 10 of 10 entries

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Gene ontology

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GO ID	GO Term
GO:0000122	negative regulation of transcription by RNA polymerase II
GO:0000187	activation of MAPK activity
GO:0001649	osteoblast differentiation
GO:0001938	positive regulation of endothelial cell proliferation
GO:0002062	chondrocyte differentiation
GO:0003130	BMP signaling pathway involved in heart induction
GO:0003308	negative regulation of Wnt signaling pathway involved in heart development
GO:0005615	extracellular space
GO:0008083	growth factor activity
GO:0008285	negative regulation of cell population proliferation
GO:0009986	cell surface
GO:0010718	positive regulation of epithelial to mesenchymal transition
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0010922	positive regulation of phosphatase activity
GO:0019211	phosphatase activator activity
GO:0021537	telencephalon development
GO:0030501	positive regulation of bone mineralization
GO:0032092	positive regulation of protein binding
GO:0032348	negative regulation of aldosterone biosynthetic process
GO:0035630	bone mineralization involved in bone maturation