| Tag | Content |
|---|---|
| Uniprot ID | E2RBJ1 |
| Entrez ID | 475379 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_532603.5 |
| Ensembl protein ID | ENSCAFP00000006972 |
| Ensembl nucleotide ID | ENSCAFG00000004681 |
| Gene name | Eukaryotic translation initiation factor 2B subunit gamma |
| Gene symbol | EIF2B3 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEFQAVVMPV GRGSRMTDLT SSIPTLLLPV GNKPLIWDPS NLLERVGFEE VIVITTRDVQ 60 KALSGEFKMK MKLDIVCIPD EADKGTADSL RQIYPKLKTD VLVLSCDLIT DVALHEVVDL 120 FRAHDASLAM LMRKGQDDLE QVPGQKGKKK AVEQRDFIGV DSTGKRLLFM ANEADLDEEL 180 VIKGSILQKH PRIHFHTGLV DAHLYCLKKY VVDFLMENKS ITSIRSELIP YLIRKQFSSA 240 SSQQGQDEKE EDLKKKELKS LDIFSFIKED NALTFAPYDA CWNVCRGERW EDLSKSQVRC 300 YVHIMKEGLC SRVSTLGLYM EANRQVPKLL SVLCPEESLI HSSAQIVNKH LIGVDSLIGP 360 DTQVGEKSSI KHSVVGSSCV IRDRVTITSC LLMNSVTVEE GSNIQGSVIC NNAVIEKGVD 420 IKNCLIGNGQ RIEAKAKRVN EVIVGSDQLM EI 452 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EIF2B3 | 475379 | E2RBJ1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | EIF2B3 | 102187733 | A0A452ERT4 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | EIF2B3 | 100065686 | F6V4Y8 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | EIF2B3 | 8891 | Q9NR50 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Eif2b3 | 108067 | B1AUN2 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | EIF2B3 | H2R941 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | EIF2B3 | 100348406 | G1T3H5 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Eif2b3 | 171145 | P70541 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | eif2b3 | 394049 | Q7ZTY5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005851 | eukaryotic translation initiation factor 2B complex |
| GO:0032045 | guanyl-nucleotide exchange factor complex |
| GO:0005085 | guanyl-nucleotide exchange factor activity |
| GO:0016779 | nucleotidyltransferase activity |
| GO:0003743 | translation initiation factor activity |
| GO:0002183 | cytoplasmic translational initiation |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| Pfam ID | Pfam Term |
|---|---|
| PF00483 | NTP_transferase |