| Tag | Content |
|---|---|
| Uniprot ID | Q7ZTY5 |
| Entrez ID | 394049 |
| Genbank protein ID | AAH52109.1 |
| Genbank nucleotide ID | NM_201074.2 |
| Ensembl protein ID | ENSDARP00000145873; ENSDARP00000016277; |
| Ensembl nucleotide ID | ENSDARG00000018106 |
| Gene name | Eukaryotic translation initiation factor 2B, subunit 3 gamma |
| Gene symbol | eif2b3 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MELQAVLMAA GGGSRMMDLT YNTPKPLLPV GNKPLIWYPL NLLERVGFEE VIVITTKEVQ 60 KALSTDQRLK TDVKMKLDVV CIQEEADMGT ADALRHIQQK IKTDILVLSC DLITDVALHE 120 VVDLFRAHNA TLSMLMSKVH EFTETVPGQK GKKKAGEQRD FVGVDVTGKR LLFMANEADL 180 EEGLVLRKSI MRKHPRMFIK TGLLDAHLYC LKRSVVDFLV HNKSVTSIRG ELVPYLVRKQ 240 FSKSLNSQHV TEDSEKNQKQ QEAHINMDLL STSKDEALLQ LARERSCWND HRGDMSEAYH 300 GGKIRCYVHI MEDGMCYRVN TLAAYIEANR VVPKLFEEPP IHPTAVVSER SLVGSDSIIG 360 PSCQISDKTS IKRSNVGTST VIKEKVKITN SIIMNGVTIE EGCNIQGSVI CSHAVIGRGA 420 DIKYCLVGSG QRVDPEAERT NEVIVGSDQL MEI 453 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EIF2B3 | 475379 | E2RBJ1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | EIF2B3 | 102187733 | A0A452ERT4 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | EIF2B3 | 100065686 | F6V4Y8 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | EIF2B3 | 8891 | Q9NR50 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Eif2b3 | 108067 | B1AUN2 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | EIF2B3 | H2R941 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | EIF2B3 | 100348406 | G1T3H5 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Eif2b3 | 171145 | P70541 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | eif2b3 | 394049 | Q7ZTY5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005851 | eukaryotic translation initiation factor 2B complex |
| GO:0032045 | guanyl-nucleotide exchange factor complex |
| GO:0005085 | guanyl-nucleotide exchange factor activity |
| GO:0016779 | nucleotidyltransferase activity |
| GO:0003743 | translation initiation factor activity |
| GO:0002183 | cytoplasmic translational initiation |
| Pfam ID | Pfam Term |
|---|---|
| PF00483 | NTP_transferase |