| Tag | Content |
|---|---|
| Uniprot ID | F6V4Y8 |
| Entrez ID | 100065686 |
| Genbank protein ID | AEP99285.1 |
| Genbank nucleotide ID | XM_005607107.2 |
| Ensembl protein ID | ENSECAP00000013286 |
| Ensembl nucleotide ID | ENSECAG00000015380 |
| Gene name | Eukaryotic translation initiation factor 2B subunit gamma |
| Gene symbol | EIF2B3 |
| Organism | Equus caballus |
| NCBI taxa ID | 9796 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEFQAVVMAV GGGSRMTDLT SSIPKPLLPV GNKPLIWYPL NLLERVGFEE VIVVTTRDVQ 60 KALCAEFKMK MKLDIVCIPD EADMGTADSL RHIYPKLKTD VLVLSCDLIT DVALHEVVDL 120 FRAHDASLAM LMRKGQDSLE PVPGQKGKKK AVEQRDFIGV DSTGKRLLFM ANEADLDEEL 180 VIKGSILQKH PRIRFHTGLV DAHLYCLKKY VVDFLMENES ITSIRSELIP YLVRKQFSSA 240 SSQQGQEEKE EDLKKKELKS LDIYSFIKEA NTLTFAPYDV CWNACQEDRR EDLSRSQVRC 300 YVHIMKEGLC SRVSTLGLYM EANRQVPKLL PILCPEESLI HSSAQIVSKH LVGVDSLIGS 360 DTQVGEKSSI KHSVIGSSCV IRDRVTITNC LLMNTVTVEE GSNIQGSVIC NNAVIEKGAD 420 IKYCLIGSGQ RIEAKAKRVN EVIVGNDQLM EI 452 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EIF2B3 | 475379 | E2RBJ1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | EIF2B3 | 102187733 | A0A452ERT4 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | EIF2B3 | 100065686 | F6V4Y8 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | EIF2B3 | 8891 | Q9NR50 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Eif2b3 | 108067 | B1AUN2 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | EIF2B3 | H2R941 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | EIF2B3 | 100348406 | G1T3H5 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Eif2b3 | 171145 | P70541 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | eif2b3 | 394049 | Q7ZTY5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005851 | eukaryotic translation initiation factor 2B complex |
| GO:0032045 | guanyl-nucleotide exchange factor complex |
| GO:0005085 | guanyl-nucleotide exchange factor activity |
| GO:0016779 | nucleotidyltransferase activity |
| GO:0003743 | translation initiation factor activity |
| GO:0002183 | cytoplasmic translational initiation |
| Pfam ID | Pfam Term |
|---|---|
| PF00483 | NTP_transferase |