Gene: EIF2B3

Basic information

Tag Content
Uniprot ID G1T3H5
Entrez ID 100348406
Genbank protein ID
Genbank nucleotide ID XM_008265354.2; XM_002715143.3;
Ensembl protein ID ENSOCUP00000010775
Ensembl nucleotide ID ENSOCUG00000012509
Gene name Eukaryotic translation initiation factor 2B subunit gamma
Gene symbol EIF2B3
Organism Oryctolagus cuniculus
NCBI taxa ID 9986
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MEFQAVVMAV GGGSRMTDLT SSIPKPLLPV GNKPLIWYPL NLLERVGFEE VIVVTTKDVQ 60
KALCAEFKMK MKPDIVCIPD EADMGTADSL RYIYPKLKTD VLVLSCDLIT DVALHEVVDL 120
FRAYDASLSM LMRKGQDGLL PVPGQKGKKK AVEQRDFIGV DSTGKRLLFM ANEADLDEEL 180
VIKGSILQKH PRIHFHTGLV DAHLYCLKKY VVDFLMENKS ITSIRSELIP YLVRKQFSSA 240
CSQQGQEEKE EDLRKKELKS LDIYSFIKEA NTLTLAPYDA CWNACRGDTW EDLSRTQVRC 300
YVHIMKEGLC SRVNTLGLYM EANRQVPKLL PVLCPEESLV HSSAQIVNKH LVGVDSLIGP 360
DTQIGEKSSI KRSVIGSSCH IKDRVTITNC LLMNSVTVEE GSSIQGSVIC NNAVIEKGAD 420
IKDCLVGSGQ RIEAKAKRMN EVIVGNDQLM EI 452

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologEIF2B3475379E2RBJ1Canis lupus familiarisPredictionMore>>
1:1 orthologEIF2B3102187733A0A452ERT4Capra hircusPredictionMore>>
1:1 orthologEIF2B3100065686F6V4Y8Equus caballusPredictionMore>>
1:1 orthologEIF2B38891Q9NR50Homo sapiensPublicationMore>>
1:1 orthologEif2b3108067B1AUN2Mus musculusPredictionMore>>
1:1 orthologEIF2B3H2R941Pan troglodytesPredictionMore>>
1:1 orthologEIF2B3100348406G1T3H5Oryctolagus cuniculusPredictionMore>>
1:1 orthologEif2b3171145P70541Rattus norvegicusPredictionMore>>
1:1 orthologeif2b3394049Q7ZTY5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005851 eukaryotic translation initiation factor 2B complex
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0016779 nucleotidyltransferase activity
GO:0003743 translation initiation factor activity
GO:0014003 oligodendrocyte development
GO:0050852 T cell receptor signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR005835 NTP_transferase_dom
IPR029044 Nucleotide-diphossugar_trans

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF00483 NTP_transferase