| Tag | Content |
|---|---|
| Uniprot ID | E2RLA0 |
| Entrez ID | 609979 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_845644.3 |
| Ensembl protein ID | ENSCAFP00000013906 |
| Ensembl nucleotide ID | ENSCAFG00000009453 |
| Gene name | ALX homeobox 4 |
| Gene symbol | ALX4 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MNAETCVSYC ESPAAAMDAY YSPVSQSREG SSPFRAYPGG DKFGTTFLSA ATKGQGFGDA 60 KSRARYGGAG QQDLAAPLES GAGARGSFNK FPPQPQPQPQ PPAPQQPQPQ QPQPPPQPPA 120 QPPHLYLQRG ACKTPPDGSL KLQEGSGGHN AALQVPCYAK ESSLGEPELP PDSDTVGMDS 180 SYLSVKEAGV KGPQDRASAD LPSPLEKADS ESNKGKKRRN RTTFTSYQLE ELEKVFQKTH 240 YPDVYAREQL AMRTDLTEAR VQVWFQNRRA KWRKRERFGQ MQQVRTHFST AYELPLLTRA 300 ENYAQIQNPS WIGNNGAASP VPACVVPCDP VPACMSPHTH PPGSGAGGVT DFLSVSGAGG 360 HVGQTHMGGL FGAAGLSPGL NGYELNGEPD RKTSSIAALR MKAKEHSAAI SWAT 414 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ALX4 | 609979 | E2RLA0 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ALX4 | A0A452E379 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ALX4 | 60529 | Q9H161 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Alx4 | 11695 | O35137 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | ALX4 | H2Q3G4 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | ALX4 | A0A287A150 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | ALX4 | 100347124 | G1SSX0 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Alx4 | 296511 | D3ZEM1 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | alx4a | 100006399 | E7FGP3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005654 | nucleoplasm |
| GO:0005634 | nucleus |
| GO:0005667 | transcription factor complex |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0071837 | HMG box domain binding |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0009952 | anterior/posterior pattern specification |
| GO:0048565 | digestive tract development |
| GO:0042733 | embryonic digit morphogenesis |
| GO:0035115 | embryonic forelimb morphogenesis |
| GO:0035116 | embryonic hindlimb morphogenesis |
| GO:0048704 | embryonic skeletal system morphogenesis |
| GO:0001942 | hair follicle development |
| GO:0007517 | muscle organ development |
| GO:0009791 | post-embryonic development |
| GO:0042981 | regulation of apoptotic process |
| GO:0060021 | roof of mouth development |