| Tag | Content |
|---|---|
| Uniprot ID | G1SSX0 |
| Entrez ID | 100347124 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_002709067.3 |
| Ensembl protein ID | ENSOCUP00000006370 |
| Ensembl nucleotide ID | ENSOCUG00000007369 |
| Gene name | ALX homeobox 4 |
| Gene symbol | ALX4 |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MNAETCVSYC ESPAAAMDAY YSPVSQSREG SSPFRGFPGG DKFGTSFLSA AAKGQAFGDA 60 KSRARYGAGQ QDLAAPLESG TGARGSFNKF QPQPPTPQPQ PPAQQPHLYM PRGACKTPPD 120 GSLKLQEGSG GHNAALQVPC YAKESSLGEP ELPPDSDPVG MDSSYLSGKE AGVKAPQERA 180 SADLPSPLEK ADSESNKGKK RRNRTTFTSY QLEELEKVFQ KTHYPDVYAR EQLAMRTDLT 240 EARVQVWFQN RRAKWRKRER FGQMQQVRTH FSTAYELPLL TRAENYAQIQ NPSWIGNNGA 300 ASPVPACVVP CDPVPACMSP HAHPPGSGAS SVTDFLSVSG AGGHVAQTHM GSLFGAAGLS 360 PGLNGYELNG EPDRKTSSIA ALRMKAKEHS AAISWAT 397 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ALX4 | 609979 | E2RLA0 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ALX4 | A0A452E379 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ALX4 | 60529 | Q9H161 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Alx4 | 11695 | O35137 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | ALX4 | H2Q3G4 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | ALX4 | A0A287A150 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | ALX4 | 100347124 | G1SSX0 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Alx4 | 296511 | D3ZEM1 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | alx4a | 100006399 | E7FGP3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005654 | nucleoplasm |
| GO:0005667 | transcription factor complex |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0071837 | HMG box domain binding |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0009952 | anterior/posterior pattern specification |
| GO:0048565 | digestive tract development |
| GO:0042733 | embryonic digit morphogenesis |
| GO:0035115 | embryonic forelimb morphogenesis |
| GO:0035116 | embryonic hindlimb morphogenesis |
| GO:0048704 | embryonic skeletal system morphogenesis |
| GO:0001942 | hair follicle development |
| GO:0007517 | muscle organ development |
| GO:0009791 | post-embryonic development |
| GO:0042981 | regulation of apoptotic process |
| GO:0060021 | roof of mouth development |