Gene: BPNT2

Basic information

Tag Content
Uniprot ID E2RMJ7
Entrez ID 477890
Genbank protein ID
Genbank nucleotide ID XM_535082.5
Ensembl protein ID ENSCAFP00000010505
Ensembl nucleotide ID ENSCAFG00000007074
Gene name Inositol monophosphatase domain containing 1
Gene symbol BPNT2
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAPMGIRLSP LGVAVFCLLG LGVLYHLYSG FLAGRFSLFG LGGEPGGGGA AGPAAAADGG 60
TVDLREMLAV SVLAAVRGGD EVRRVRESNV LHEKSKGKTR EGAEDKMTSG DVLSNRKMFY 120
LLKTAFPSVQ INTEEHVDAA DQEVILWDHK IPEDILKEIA TPKEVPAESV TVWIDPLDAT 180
QEYTEDLRKY VTTMVCVAVN GKPVLGVIHK PFSEYTAWAM VDGGSNVKAR TSYNEKTPRI 240
IVSRSHSGMV KQVALQTFGN QTTIIPAGGA GYKVLALLDV PDKSQEKADL YIHVTYIKKW 300
DICAGNAILK ALGGHMTTLS GEEISYTGSD GIEGGLLASI RMNHQALVRK LPDLDKTGHK 360

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologBPNT2532797Q2KJ53Bos taurusPredictionMore>>
1:1 orthologBPNT2477890E2RMJ7Canis lupus familiarisPredictionMore>>
1:1 orthologIMPAD1A0A452ECA6Capra hircusPredictionMore>>
1:1 orthologBPNT254928Q9NX62Homo sapiensPredictionMore>>
1:1 orthologBpnt2242291Q80V26CPOMus musculusPublicationMore>>
1:1 orthologBPNT2100156925F1RT67Sus scrofaPredictionMore>>
1:1 orthologIMPAD1100343037G1SLS8Oryctolagus cuniculusPredictionMore>>
1:1 orthologbpnt2641570Q2YDR3Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005829 cytosol
GO:0012505 endomembrane system
GO:0016021 integral component of membrane
GO:0016604 nuclear body
GO:0032588 trans-Golgi network membrane
GO:0097657 3',5'-nucleotide bisphosphate phosphatase activity
GO:0008254 3'-nucleotidase activity
GO:0002063 chondrocyte development
GO:0030204 chondroitin sulfate metabolic process
GO:0042733 embryonic digit morphogenesis
GO:0001958 endochondral ossification
GO:0046855 inositol phosphate dephosphorylation
GO:0046854 phosphatidylinositol phosphorylation
GO:0009791 post-embryonic development
GO:0001501 skeletal system development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR000760 Inositol_monophosphatase-like
IPR020550 Inositol_monophosphatase_CS

PROSITE

PROSITE ID PROSITE Term
PS00630 IMP_2

Pfam

Pfam ID Pfam Term
PF00459 Inositol_P