Gene: IMPAD1

Basic information

Tag Content
Uniprot ID G1SLS8
Entrez ID 100343037
Genbank protein ID
Genbank nucleotide ID XM_002710504.3
Ensembl protein ID ENSOCUP00000003826
Ensembl nucleotide ID ENSOCUG00000004428
Gene name Inositol monophosphatase domain containing 1
Gene symbol IMPAD1
Organism Oryctolagus cuniculus
NCBI taxa ID 9986
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAPMGIRLSP LGVAVFCLLG LGVLYHLYSG FLAGRFSVFG MGGEPAGGAA GPAAAADGGT 60
VDLREMLAVS VLAAMRGGDE VRRVRESNVL HEKSKGKTRE GAEDKMTSGD VLSNRKMFYL 120
LKTAFPSVQI NTEEHVDATD QEVILWDRKI PEDILKEITT SKEVPAESVT VWIDPLDATQ 180
EYTEDLRKYV TTMVCVAVNG KPVLGVIHKP FSEYTAWAMV DGGSNVKARS SYNEKTPRIV 240
VSRSHAGMVK QVALQTFGNQ TTIIAAGGAG YKVLALLDVP DQNQEKADLY IHVTYIKKWD 300
ICAGNAILKA LGGHMTTLNG EEISYTGSDG IEGGLLASIR MNHQALIRKL PDLEKTGHK 359

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologBPNT2532797Q2KJ53Bos taurusPredictionMore>>
1:1 orthologBPNT2477890E2RMJ7Canis lupus familiarisPredictionMore>>
1:1 orthologIMPAD1A0A452ECA6Capra hircusPredictionMore>>
1:1 orthologBPNT254928Q9NX62Homo sapiensPredictionMore>>
1:1 orthologBpnt2242291Q80V26CPOMus musculusPublicationMore>>
1:1 orthologBPNT2100156925F1RT67Sus scrofaPredictionMore>>
1:1 orthologIMPAD1100343037G1SLS8Oryctolagus cuniculusPredictionMore>>
1:1 orthologbpnt2641570Q2YDR3Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016021 integral component of membrane
GO:0046855 inositol phosphate dephosphorylation
GO:0046854 phosphatidylinositol phosphorylation

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR000760 Inositol_monophosphatase-like
IPR020550 Inositol_monophosphatase_CS

PROSITE

PROSITE ID PROSITE Term
PS00630 IMP_2

Pfam

Pfam ID Pfam Term
PF00459 Inositol_P