| Tag | Content |
|---|---|
| Uniprot ID | F1MB04 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSBTAP00000021099 |
| Ensembl nucleotide ID | ENSBTAG00000015874 |
| Gene name | Caspase-3 |
| Gene symbol | CASP3 |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MENTENSVDS KSIKTSETKI LHGSKSMDSG ISLEESYKMD YPEMGLCIII NNKNFHENTG 60 MACRSGTDVD AANLRETFMN LKYEVRIKND LTCKEMLELM SNVSKEDHSK RSSFICVLLS 120 HGEEGIIFGT NGPVNLKKLA SFFRGDYCRS LTGKPKLFII QACRGTELDC GIETDSGAED 180 DMACQKIPVE ADFLYAYSTA PGYFSWRNAK NGSWFIQVLC EMLKKYAHRL ELMHILTRVN 240 RKVAIEYESF STDSAFHAKK QIPCIMSMLT KELYF 275 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CASP3 | F1MB04 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | CASP3 | 102177031 | H9B8T7 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | CASP3 | 100034083 | F7A730 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | CASP3 | 836 | P42574 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Casp3 | 12367 | P70677 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | CASP3 | 461669 | Q5IS54 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Casp3 | 25402 | P55213 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005829 | cytosol |
| GO:0005634 | nucleus |
| GO:0004190 | aspartic-type endopeptidase activity |
| GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity |
| GO:0097153 | cysteine-type endopeptidase activity involved in apoptotic process |
| GO:0097199 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway |
| GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis |
| GO:0061713 | anterior neural tube closure |
| GO:0006915 | apoptotic process |
| GO:0001782 | B cell homeostasis |
| GO:0045165 | cell fate commitment |
| GO:0006974 | cellular response to DNA damage stimulus |
| GO:0072734 | cellular response to staurosporine |
| GO:0030218 | erythrocyte differentiation |
| GO:0034349 | glial cell apoptotic process |
| GO:0007507 | heart development |
| GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress |
| GO:0030216 | keratinocyte differentiation |
| GO:0046007 | negative regulation of activated T cell proliferation |
| GO:0043066 | negative regulation of apoptotic process |
| GO:0030889 | negative regulation of B cell proliferation |
| GO:0051402 | neuron apoptotic process |
| GO:0030182 | neuron differentiation |
| GO:0048011 | neurotrophin TRK receptor signaling pathway |
| GO:1902004 | positive regulation of amyloid-beta formation |
| GO:0043065 | positive regulation of apoptotic process |
| GO:0016485 | protein processing |
| GO:0031647 | regulation of protein stability |
| GO:0009411 | response to UV |
| GO:0009611 | response to wounding |
| GO:0007605 | sensory perception of sound |
| GO:0043029 | T cell homeostasis |