| Tag | Content |
|---|---|
| Uniprot ID | F1N6X2 |
| Entrez ID | 512459 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001205723.1 |
| Ensembl protein ID | ENSBTAP00000010598 |
| Ensembl nucleotide ID | ENSBTAG00000008056 |
| Gene name | Glutamate decarboxylase 2 |
| Gene symbol | GAD2 |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MASPGSGFWS FGSEDGSGDP ENPGTARAWC QVAQKFTGGI GNKLCALLYG DAEKPAESSG 60 SQPPRATSRK AACSCNQKPC SCPKAEVNYA FLHATDLLPA CDGERPTLAF LQEVMDILLQ 120 YVVKSFDRST KVIDFHYPNE LLQEYNWELA DQPQNLEEIL MHCQTTLKYA IKTGHPRYFN 180 QLSTGLDMVG LAADWLTSTA NTNMFTYEIA PVFVLLEYVT LKKMREIIGW PGGSGDGIFS 240 PGGAISNMYA MLIARFKMFP EVKEKGMAAV PRLIAFTSEH SHFSLKKGAA ALGIGTDSVI 300 LIKCDERGKM IPSDLERRIL EAKQKGFVPF LVSATAGTTV YGAFDPLLAV ADICKKYKIW 360 MHVDAAWGGG LLMSRKHKWK LSGVERANSV TWNPHKMMGV PLQCSALLVR EEGLMQSCNQ 420 MHASYLFQQD KHYDLSYDTG DKALQCGRHV DVFKLWLMWR AKGTIGFEAH IDKCLELAEY 480 LYNIIKNREG YEMVFDGKPQ HTNVCFWYVP PSLRVLDNNE ERLSRLSKVA PMIKARMMES 540 GTTMVSYQPL GDKVNFFRMV ISNPAATHQD IDFLIEEIER LGQDL 585 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GAD2 | 512459 | F1N6X2 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | GAD2 | F1PV66 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | GAD2 | 102178638 | A0A452FGS2 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GAD2 | 100055419 | F7D4X1 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | GAD2 | 2572 | Q05329 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Gad2 | 14417 | P48320 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GAD2 | H2Q1R2 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | GAD2 | A0A2C9F3C1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | GAD2 | 100339011 | G1TDS5 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Gad2 | 24380 | Q05683 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | gad2 | 550403 | F1R9E8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0030424 | axon |
| GO:0005737 | cytoplasm |
| GO:0045202 | synapse |
| GO:0016831 | carboxy-lyase activity |
| GO:0030170 | pyridoxal phosphate binding |
| GO:0019752 | carboxylic acid metabolic process |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00392 | DDC_GAD_HDC_YDC |
| Pfam ID | Pfam Term |
|---|---|
| PF00282 | Pyridoxal_deC |