| Tag | Content |
|---|---|
| Uniprot ID | F1R9E8 |
| Entrez ID | 550403 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001017708.2 |
| Ensembl protein ID | ENSDARP00000010443 |
| Ensembl nucleotide ID | ENSDARG00000015537 |
| Gene name | Glutamate decarboxylase 2 |
| Gene symbol | gad2 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MASHGFWFLG AENAAGNGSQ SPNTPRAWCQ AAAQKFSGGI GSKLCALLNV GEAEKAAQAP 60 VKAEDESTAE SCGCNKPCNC SKATACFSDL YSTDLLPALD GDAKTMNFLQ EVVDILLAYI 120 VESFDRSTKV IDFHYPNELL QRNNWELSDE PETLDDILIS CRATLKYAIK TAHPRYFNQL 180 STGLDMVGLA ADWLTSTANT NMFTYEVAPV FVLLEYVTLK KMREIIGWQD GHGDGIFSPG 240 GAISNMYAML LARYKMFPEV KEKGMSSVPR LVAFTSEHSH FSIKKGAAAL GIGTESVICI 300 KADERGKMIP SDLERRIIEA KQKGYVPFFV SATAGTTVYG AFDPLIAIAD ICKKHDVWMH 360 VDGAWGGSLL MSRKHRWKLN GVERANSMTW NPHKMMAVPL QCSALLVREE GLMQSCNQMQ 420 ACYLFQQDKH YDLQYDTGDK ALQCGRHVDI FKLWLMWRAK GTIGFEAQID KCLELSEYLY 480 NKIKDREGYQ MVFDGKPQHT NVCFWYLPPG VRYLEDKVER MKRLHKVAPV IKARMMEYGT 540 TMVSYQPQGD KVNFFRMVIS NPAATFEDID FLIEEIERLG QDL 583 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GAD2 | 512459 | F1N6X2 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | GAD2 | F1PV66 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | GAD2 | 102178638 | A0A452FGS2 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GAD2 | 100055419 | F7D4X1 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | GAD2 | 2572 | Q05329 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Gad2 | 14417 | P48320 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GAD2 | H2Q1R2 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | GAD2 | A0A2C9F3C1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | GAD2 | 100339011 | G1TDS5 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Gad2 | 24380 | Q05683 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | gad2 | 550403 | F1R9E8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016831 | carboxy-lyase activity |
| GO:0030170 | pyridoxal phosphate binding |
| GO:0009449 | gamma-aminobutyric acid biosynthetic process |
| GO:0042136 | neurotransmitter biosynthetic process |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00392 | DDC_GAD_HDC_YDC |
| Pfam ID | Pfam Term |
|---|---|
| PF00282 | Pyridoxal_deC |