| Tag | Content |
|---|---|
| Uniprot ID | H2Q1R2 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000004016 |
| Ensembl nucleotide ID | ENSPTRG00000002372 |
| Gene name | Glutamate decarboxylase 2 |
| Gene symbol | GAD2 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MASPGSGFWS FGSEDGSGDS ENPGTARAWC QVAQKFTGGI GNKLCALLYG DAEKPAESGG 60 SQPPRAAARK AACTCDQKPC SCSKVDVNYA FLHATDLLPA CDGERPTLAF LQDVMNILLQ 120 YVVKSFDRST KVIDFHYPNE LLQEYNWELA DQPQNLEEIL MHCQTTLKYA IKTGHPRYFN 180 QLSTGLDMVG LAADWLTSTA NTNMFTYEIA PVFVLLEYVT LKKMREIIGW PGGSGDGIFS 240 PGGAISNMYA MMIARFKMFP EVKEKGMAAV PRLIAFTSEH SHFSLKKGAA ALGIGTDSVI 300 LIKCDERGKM IPSDLERRIL EAKQKGFVPF LVSATAGTTV YGAFDPLLAV ADICKKYKIW 360 MHVDAAWGGG LLMSRKHKWK LSGVERANSV TWNPHKMMGV PLQCSALLVR EEGLMQNCNQ 420 MHASYLFQQD KHYDLSYDTG DKALQCGRHV DVFKLWLMWR AKGTTGFEAH VDKCLELAEY 480 LYNIIKNREG YEMVFDGKPQ HTNVCFWYIP PSLRTLEDNE ERMSRLSKVS VICPPWPPKV 540 LRLQA 545 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GAD2 | 512459 | F1N6X2 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | GAD2 | F1PV66 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | GAD2 | 102178638 | A0A452FGS2 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GAD2 | 100055419 | F7D4X1 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | GAD2 | 2572 | Q05329 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Gad2 | 14417 | P48320 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GAD2 | H2Q1R2 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | GAD2 | A0A2C9F3C1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | GAD2 | 100339011 | G1TDS5 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Gad2 | 24380 | Q05683 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | gad2 | 550403 | F1R9E8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016831 | carboxy-lyase activity |
| GO:0030170 | pyridoxal phosphate binding |
| GO:0019752 | carboxylic acid metabolic process |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00392 | DDC_GAD_HDC_YDC |
| Pfam ID | Pfam Term |
|---|---|
| PF00282 | Pyridoxal_deC |