| Tag | Content |
|---|---|
| Uniprot ID | F1PV66 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCAFP00000006413 |
| Ensembl nucleotide ID | ENSCAFG00000004299 |
| Gene name | Glutamate decarboxylase 2 |
| Gene symbol | GAD2 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MASPGSGFWS FGSEDGSGDP ENPSTARAWC QVAQKFTGGI GNKLCALLYG DAEKPAESGG 60 SEPPRATSRK AACACNQKPC SCPKAEVNYA FLHATDLLPA CDGERPTLAF LQDVMDILLQ 120 YVVKSFDRST KVIDFHYPNE LLQEYNWELA DQPQNLEEIL MHCQTTLKYA IKTGHPRYFN 180 QLSTGLDMVG LAADWLTSTA NTNMFTYEIA PVFVLLEYVT LKKMREIIGW PGGSGDGIFS 240 PGGAISNMYA MLIARFKMFP EVKEKGMAAV PRLIAFTSEH SHFSLKKGAA ALGIGTDSVI 300 LIKCDERGKM VPSDLERRIL EAKQKGFVPF LVSATAGTTV YGAFDPLLAV ADICKKYKIW 360 MHVDAAWGGG LLMSRKHKWK LSGVERANCG TWNPHKMMGV PLQCSALRVR EEGLMQSCNQ 420 MHASYLFQQD KHYDLSYDTG DKALQCGRHV DVFKLWLMWR AKGTTGFEAH IDKCLELAEY 480 LYSIIKNREG YEMVFDGKPQ HTNVCFWYVP PSLRVLEDNE ERMNRLSKVA PVIKARMMEY 540 GTTMVSYQPL GDKVNFFRMV ISNPAATHQD IDFLIEEIER LGQDL 585 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GAD2 | 512459 | F1N6X2 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | GAD2 | F1PV66 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | GAD2 | 102178638 | A0A452FGS2 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GAD2 | 100055419 | F7D4X1 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | GAD2 | 2572 | Q05329 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Gad2 | 14417 | P48320 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GAD2 | H2Q1R2 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | GAD2 | A0A2C9F3C1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | GAD2 | 100339011 | G1TDS5 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Gad2 | 24380 | Q05683 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | gad2 | 550403 | F1R9E8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0030424 | axon |
| GO:0005737 | cytoplasm |
| GO:0045202 | synapse |
| GO:0016831 | carboxy-lyase activity |
| GO:0030170 | pyridoxal phosphate binding |
| GO:0019752 | carboxylic acid metabolic process |
| Pfam ID | Pfam Term |
|---|---|
| PF00282 | Pyridoxal_deC |