| Tag | Content |
|---|---|
| Uniprot ID | F1P6A2 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005634678.2 |
| Ensembl protein ID | ENSCAFP00000014582 |
| Ensembl nucleotide ID | ENSCAFG00000009905 |
| Gene name | Matrix metalloproteinase-9 |
| Gene symbol | MMP9 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSPRQPLVLV FLVLGCCSAA PRPHKPTVVV FPGDLRTNLT DKQLAEEYLF RYGYTQVAEL 60 SNDKQSLSRG LRLLQRRLAL PETGELDKTT LEAMRAPRCG VPDLGKFQTF EGDLKWHHND 120 ITYWIQNYSE DLPRDVIDDA FARAFAVWSA VTPLTFTRVY GPEADIIIQF GVREHGDGYP 180 FDGKNGLLAH AFPPGPGIQG DAHFDDEELW TLGKGVVVPT HFGNADGAPC HFPFTFEGRS 240 YSACTTDGRS DDTPWCSTTA DYDTDRRFGF CPSEKLYTQD GNGDGKPCVF PFTFEGRSYS 300 TCTTDGRSDG YRWCSTTADY DQDKLYGFCP TRVDSAVTGG NSAGEPCVFP FIFLGKQYST 360 CTREGRGDGH LWCATTSNFD RDKKWGFCPD QGYSLFLVAA HEFGHALGLD HSSVPEALMY 420 PMYSFTEGPP LHEDDVRGIQ HLYGPRPEPE PQPPTAPPTA PPTVCATGPP TTRPSERPTA 480 GPTGPPAAGP TGPPTAGPSE APTVPVDPAE DICKVNIFDA IAEIRNYLHF FKEGKYWRFS 540 KGKGRRVQGP FLITDTWPAL PRKLDSAFED GLTKKTFFFS GRQVWVYTGT SVVGPRRLDK 600 LGLGPEVTQV TGALPQGGGK VLLFSRQRFW SFDVKTQTVD PRSAGSVEQM YPGVPLNTHD 660 IFQYQEKAYF CQDRFYWRVN SRNEVNQVDE VGYVTFDILQ CPED 704 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MMP9 | F1P6A2 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | MMP9 | A0A452EYC3 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | MMP9 | 4318 | P14780 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Mmp9 | 17395 | P41245 | E12.5, E13.5, E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | MMP9 | 458294 | H2QKI0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | MMP9 | A0A287AZD5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Mmp9 | D3ZYK8 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | mmp9 | F1QC76 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0031012 | extracellular matrix |
| GO:0004222 | metalloendopeptidase activity |
| GO:0008270 | zinc ion binding |
| InterPro ID | InterPro Term |
|---|---|
| IPR000562 | FN_type2_dom |
| IPR036943 | FN_type2_sf |
| IPR000585 | Hemopexin-like_dom |
| IPR036375 | Hemopexin-like_dom_sf |
| IPR018487 | Hemopexin-like_repeat |
| IPR018486 | Hemopexin_CS |
| IPR013806 | Kringle-like |
| IPR033739 | M10A_MMP |
| IPR024079 | MetalloPept_cat_dom_sf |
| IPR001818 | Pept_M10_metallopeptidase |
| IPR021190 | Pept_M10A |
| IPR021158 | Pept_M10A_Zn_BS |
| IPR006026 | Peptidase_Metallo |
| IPR002477 | Peptidoglycan-bd-like |
| IPR036365 | PGBD-like_sf |
| IPR036366 | PGBDSf |
| IPR006970 | PT |