| Tag | Content |
|---|---|
| Uniprot ID | F1QC76 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000062844 |
| Ensembl nucleotide ID | ENSDARG00000042816 |
| Gene name | 92 kDa gelatinase |
| Gene symbol | mmp9 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRLGVLAFLV LGTCSLRAWC LPLKSVFVTF PGDVIKNMTN TQLADEYLKR YGYIDVLQRS 60 GLQAVVSNTK ALKKLQRQLG LEETGLLDQP TVDAMKQPRC GVPDIRNYKT FDGDLKWDHT 120 DVTYRILNYS PDMEASLIDD AFARAFKVWS DVTPLTFTRL FDGIADIMIS FGKADHGDPY 180 PFDGKDGLLA HAYPPGEGTQ GDAHFDDDEY WTLGSGPAIQ TRYGNAEGAM CHFPFLFEGT 240 SYSTCTTEGR TDGLPWCSTT ADYDKDKKFG FCPSELLFTF DGNSNEAPCV FPFIFDGKKY 300 DSCTTEGRND GYRWCSTTAN FDTDKKYGFC PNRDTAVIGG NSEGEPCHFP FTFLGNTYSS 360 CTSEGRNDGK LWCGTTSNYD TDKKWGFCPD RGYSLFLVAA HEFGHALGLD HSNIKDALMY 420 PMYKYVEGFP LHRDDIDGIQ YLYGPRTGPE PTAPQPRTTT SSPVVPTKPS PSDKTTTAST 480 TTQVVPSDDA CQIKEFDAIT EIQKELHFFK DGRYWKISGN GERKGPFMIS AKWPALPAVI 540 NSAFEDHLTK KIYFFSERQF WVYSGNDVLG PRKIEKLGLP SDLDKVEGSM QRGKGKVLLF 600 NGENFWRLDV KAQLIDRGYP RFTDAAFGGV PVDSHDVFLY KGFFYFCRES FYWRMNAKRQ 660 VDRVGYVKYD LLKCSDIHSL |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MMP9 | F1P6A2 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | MMP9 | A0A452EYC3 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | MMP9 | 4318 | P14780 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Mmp9 | 17395 | P41245 | E12.5, E13.5, E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | MMP9 | 458294 | H2QKI0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | MMP9 | A0A287AZD5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Mmp9 | D3ZYK8 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | mmp9 | F1QC76 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0031012 | extracellular matrix |
| GO:0005576 | extracellular region |
| GO:0004222 | metalloendopeptidase activity |
| GO:0008270 | zinc ion binding |
| GO:0030574 | collagen catabolic process |
| GO:0030199 | collagen fibril organization |
| GO:0060429 | epithelium development |
| GO:0030198 | extracellular matrix organization |
| GO:0033334 | fin morphogenesis |
| GO:0031101 | fin regeneration |
| GO:0003417 | growth plate cartilage development |
| GO:0035701 | hematopoietic stem cell migration |
| GO:0090594 | inflammatory response to wounding |
| GO:0050900 | leukocyte migration |
| GO:0001503 | ossification |
| GO:0002633 | positive regulation of granuloma formation |
| GO:0009617 | response to bacterium |
| GO:0042060 | wound healing |
| InterPro ID | InterPro Term |
|---|---|
| IPR000562 | FN_type2_dom |
| IPR036943 | FN_type2_sf |
| IPR000585 | Hemopexin-like_dom |
| IPR036375 | Hemopexin-like_dom_sf |
| IPR018487 | Hemopexin-like_repeat |
| IPR013806 | Kringle-like |
| IPR033739 | M10A_MMP |
| IPR024079 | MetalloPept_cat_dom_sf |
| IPR028688 | MMP9 |
| IPR001818 | Pept_M10_metallopeptidase |
| IPR021190 | Pept_M10A |
| IPR021158 | Pept_M10A_Zn_BS |
| IPR006026 | Peptidase_Metallo |
| IPR002477 | Peptidoglycan-bd-like |
| IPR036365 | PGBD-like_sf |
| IPR036366 | PGBDSf |