| Tag | Content |
|---|---|
| Uniprot ID | F1Q989 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000115239 |
| Ensembl nucleotide ID | ENSDARG00000076994 |
| Gene name | Adhesion G protein-coupled receptor A2 |
| Gene symbol | adgra2 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | XNLSNNRIRM LKNGSFAGLS SLEKLDLRNN LISTIMPGAF LGLTALRKLD LSSNRIGCLT 60 PEMFQGLTNL TKLNISGNIF SSLDPNVFME LHSLKLVNFH SEFLSCDCGL RWVPSFFRSG 120 SARLGDETLC AYPRRLQNKP LRLLRESDLS CEGPLELHTL SLLPSQRQVV FKGDRLPFHC 180 TASLVDKITA LHWRQNGQPV TSDPTKGIHL EESVQHDCTF ITSELILSNV HVEASGEWEC 240 VVSTGRGNTS CSVEIVVLEN SASFCPEQKV NNNRGEFRWP RTLAGITSYQ HCLQLRYPSL 300 TLGGGVEQKK ASRNCDRSGR WEEADYSQCL YTNDITRILH TFILMPVNAS NAVTLAHQVR 360 SYTLEAAGFT DTVDVLYVAQ MMHKFMDYVT ELRELSEVLV EMGSNLMQVD DQILARAQRE 420 ERACSSIVYT LETLAWPQLH SHAQDLSRYS RNIVMEAHLI RPAHFTGISC TVYQRREGAA 480 GSQVHDGADL SLEQQLRFRC TTGTHNTSLN AFHLKNAVAL ATVSLPATLF PPNAPPDCKL 540 QFVAFRNGRF FPFTSNFTGH SDLARRRGIS TPVIYAGLDG CSMWNQSDPI IVSLRHTSPG 600 HDPVAAHWNS QALGHHGSWS LDGCQLIHSD VSISTLRCSV LSNYAVLQEI PDFPGSPSIP 660 VEVLHPVIYT CTAVLLLCLF TIIITYILHH SSIRITRKSW HTLLNTSFHV AMTSAVFAGG 720 ITLTGYPIVC QAVRIVLHYS SLSTLLWIGV SARVIYKEAL LRTPQQLEGE SAVQPTQRPM 780 LRFYLIAGGV PLIICGITAA VNINNYGDNI PYCWLVWQPS FGAFYIPAGL IILVTWIYFL 840 CTVFCLRQRN FQESKDLQCS ASDPSNLPES QPALSGSTSL LSTDSGVSPV HAGTTVEDQY 900 SLKVQCLALM ATQFVFVGLW CCGAMAVWHV DRERKLFSCL YGGTATGLGI FLVLHHCFKR 960 LDVQAAWLGC CPG 973 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ADGRA2 | 102178880 | A0A452EYM7 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ADGRA2 | 25960 | Q96PE1 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Adgra2 | 78560 | Q91ZV8 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ADGRA2 | 472739 | H2QW10 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Adgra2 | D4ADC7 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | adgra2 | F1Q989 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0004930 | G protein-coupled receptor activity |
| GO:0007166 | cell surface receptor signaling pathway |
| InterPro ID | InterPro Term |
|---|---|
| IPR000483 | Cys-rich_flank_reg_C |
| IPR017981 | GPCR_2-like |
| IPR036445 | GPCR_2_extracell_dom_sf |
| IPR001879 | GPCR_2_extracellular_dom |
| IPR000832 | GPCR_2_secretin-like |
| IPR000203 | GPS |
| IPR007110 | Ig-like_dom |
| IPR036179 | Ig-like_dom_sf |
| IPR013783 | Ig-like_fold |
| IPR003599 | Ig_sub |
| IPR001611 | Leu-rich_rpt |
| IPR003591 | Leu-rich_rpt_typical-subtyp |
| IPR032675 | LRR_dom_sf |