| Tag | Content |
|---|---|
| Uniprot ID | G1T8L9 |
| Entrez ID | 100351275 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_002716975.3 |
| Ensembl protein ID | ENSOCUP00000012928 |
| Ensembl nucleotide ID | ENSOCUG00000015048 |
| Gene name | Serine/threonine-protein kinase receptor |
| Gene symbol | BMPR1B |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGWLEELRGQ LPISSVILLS VHARANFLDN MLLRSSGKLN VGTKKEDGES TAPTPRPKIL 60 RCKCHHHCPE DSVNNICSTD GYCFTMIEED DSGMPVVTSG CLGLEGSDFQ CRDTPIPHQR 120 RSIECCTERN ECNKDLHPTL PPLKNRDFVD GPIHHKALLI SVTVCSLLLV LIILFCYFRY 180 KRQETRPRYS IGLEQDETYI PPGESLRDLI EQSQSSGSGS GLPLLVQRTI AKQIQMVKQI 240 GKGRYGEVWM GKWRGEKVAV KVFFTTEEAS WFRETEIYQT VLMRHENILG FIAADIKGTG 300 SWTQLYLITD YHENGSLYDY LKSTTLDTKS MLKLAYSSVS GLCHLHTEIF STQGKPAIAH 360 RDLKSKNILV KKNGTCCIAD LGLAVKFISD TNEVDIPPNT RVGTKRYMPP EVLDESLNRN 420 HFQSYIMADM YSFGLILWEI ARRCVSGGIV EEYQLPYHDL VPSDPSYEDM REIVCIKKLR 480 PSFPNRWSSD ECLRQMGKLM TECWAHNPAS RLTALRVKKT LAKMSESQDI KL 532 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BMPR1B | 407128 | A7YWG6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | BMPR1B | 100861211 | B5AFX6 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | BMPR1B | 658 | O00238 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Bmpr1b | 12167 | P36898 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BMPR1B | 396691 | Q95L23 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | BMPR1B | 100351275 | G1T8L9 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Bmpr1b | 310914 | M0R3J4 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005524 | ATP binding |
| GO:0046872 | metal ion binding |
| GO:0004675 | transmembrane receptor protein serine/threonine kinase activity |
| GO:0002063 | chondrocyte development |
| GO:0060350 | endochondral bone morphogenesis |
| GO:1902731 | negative regulation of chondrocyte proliferation |
| GO:0061036 | positive regulation of cartilage development |
| GO:0030166 | proteoglycan biosynthetic process |
| Keyword ID | Keyword Term |
|---|---|
| KW-0067 | ATP-binding |
| KW-0418 | Kinase |
| KW-0460 | Magnesium |
| KW-0464 | Manganese |
| KW-0472 | Membrane |
| KW-0479 | Metal-binding |
| KW-0547 | Nucleotide-binding |
| KW-0675 | Receptor |
| KW-1185 | Reference proteome |
| KW-0723 | Serine/threonine-protein kinase |
| KW-0808 | Transferase |
| KW-0812 | Transmembrane |
| KW-1133 | Transmembrane helix |