| Tag | Content |
|---|---|
| Uniprot ID | M0R3J4 |
| Entrez ID | 310914 |
| Genbank protein ID | EDL82342.1 |
| Genbank nucleotide ID | XM_017590942.1; XM_006233401.3; XM_006233400.3; XM_017590940.1; XM_017590941.1; |
| Ensembl protein ID | ENSRNOP00000021963 |
| Ensembl nucleotide ID | ENSRNOG00000016289 |
| Gene name | Serine/threonine-protein kinase receptor |
| Gene symbol | Bmpr1b |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MLLRSSGKLN VGTKKEDGES TAPTARPKVL RCKCHHHCPE DSVNNICSTD GYCFTMIEED 60 DSGTPVVTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN ECNKDLHPTL PPLKDRDFVD 120 GPIHHKALLI SVTVCSLLLV LIILFCYFRY KRQEARPRYS IGLEQDETYI PPGESLRDLI 180 EQSQSSGSGS GLPLLVQRTI AKQIQMVKQI GKGRYGEVWM GKWRGEKVAV KVFFTTEEAS 240 WFRETEIYQT VLMRHENILG FIAADIKGTG SWTQLYLITD YHENGSLYDY LKSTTLDAKS 300 MLKLAYSSVS GLCHLHTEIF STQGKPAIAH RDLKSKNILV KKNGTCCIAD LGLAVKFISD 360 TNEVDIPPNT RVGTKRYMPP EVLDESLNRT HFQSYIMADM YSFGLILWEI ARRCVSGGIV 420 EEYQLPYHDL VPSDPSYEDM REIVCMKKLR PSFPNRWSSD ECLRQMGKLM TECWAHNPAS 480 RLTALRVKKT LAKMSESQDI KL 502 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BMPR1B | 407128 | A7YWG6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | BMPR1B | 100861211 | B5AFX6 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | BMPR1B | 658 | O00238 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Bmpr1b | 12167 | P36898 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BMPR1B | 396691 | Q95L23 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | BMPR1B | 100351275 | G1T8L9 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Bmpr1b | 310914 | M0R3J4 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0030425 | dendrite |
| GO:0016021 | integral component of membrane |
| GO:0043025 | neuronal cell body |
| GO:0005886 | plasma membrane |
| GO:0043235 | receptor complex |
| GO:0005524 | ATP binding |
| GO:0046872 | metal ion binding |
| GO:0004674 | protein serine/threonine kinase activity |
| GO:0046332 | SMAD binding |
| GO:0005025 | transforming growth factor beta receptor activity, type I |
| GO:0004675 | transmembrane receptor protein serine/threonine kinase activity |
| GO:0030509 | BMP signaling pathway |
| GO:0043010 | camera-type eye development |
| GO:0001502 | cartilage condensation |
| GO:0030154 | cell differentiation |
| GO:0071773 | cellular response to BMP stimulus |
| GO:0071363 | cellular response to growth factor stimulus |
| GO:0002062 | chondrocyte differentiation |
| GO:0009953 | dorsal/ventral pattern formation |
| GO:0001654 | eye development |
| GO:0006954 | inflammatory response |
| GO:0035108 | limb morphogenesis |
| GO:0001550 | ovarian cumulus expansion |
| GO:0042698 | ovulation cycle |
| GO:0030501 | positive regulation of bone mineralization |
| GO:0045597 | positive regulation of cell differentiation |
| GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors |
| GO:0045669 | positive regulation of osteoblast differentiation |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0006468 | protein phosphorylation |
| GO:0060041 | retina development in camera-type eye |
| GO:0031290 | retinal ganglion cell axon guidance |
| GO:0001501 | skeletal system development |
| GO:0007178 | transmembrane receptor protein serine/threonine kinase signaling pathway |
| Keyword ID | Keyword Term |
|---|---|
| KW-0067 | ATP-binding |
| KW-0418 | Kinase |
| KW-0460 | Magnesium |
| KW-0464 | Manganese |
| KW-0472 | Membrane |
| KW-0479 | Metal-binding |
| KW-0547 | Nucleotide-binding |
| KW-0675 | Receptor |
| KW-1185 | Reference proteome |
| KW-0723 | Serine/threonine-protein kinase |
| KW-0808 | Transferase |
| KW-0812 | Transmembrane |
| KW-1133 | Transmembrane helix |