| Tag | Content |
|---|---|
| Uniprot ID | Q95L23; I3LIC3; K7GQX2; |
| Entrez ID | 396691 |
| Genbank protein ID | ABD46948.1; HDB04585.1; ADX01190.1; AAL47544.1; AAL27463.1; |
| Genbank nucleotide ID | NM_001039745.1 |
| Ensembl protein ID | ENSSSCP00000030296 |
| Ensembl nucleotide ID | ENSSSCG00000029621 |
| Gene name | Receptor protein serine/threonine kinase |
| Gene symbol | BMPR1B |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MLLRSSGKLN VGTKKEDGES TAPTPRPKIL RCKCHHHCPE DSVNNICSTD GYCFTMIEED 60 DSGMPVVTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN ECNKDLHPTL PPLKTRDFVD 120 GPIHHKALLI SVTVCSLLLV LIILFCYFRY KRQETRPRYS IGLEQDETYI PPGESLRDLI 180 EQSQSSGSGS GLPLLVQRTI AKQIQMVKQI GKGRYGEVWM GRWRGEKVAV KVFFTTEEAS 240 WFRETEIYQT VLMRHENILG FIAADIKGTG SWTQLYLITD YHENGSLYDY LKSTTLDTKS 300 MLKLAYSSVS GLCHLHTEIF STQGKPAIAH RDLKSKNILV KKNGTCCIAD LGLAVKFISD 360 TNEVDIPPNT RVGTKRYMAP EVLDESLNRN HFQSYIMADM YSFGLILWEV ARRCVSGGIV 420 EEYQLPYHDL VPSDPSYEDM REIVCIKKLR PSFPNRWSSD ECLRQMGKLM TECWAQNPAS 480 RLTALRVKKT LAKMSESQDI KL 502 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BMPR1B | 407128 | A7YWG6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | BMPR1B | 100861211 | B5AFX6 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | BMPR1B | 658 | O00238 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Bmpr1b | 12167 | P36898 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BMPR1B | 396691 | Q95L23 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | BMPR1B | 100351275 | G1T8L9 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Bmpr1b | 310914 | M0R3J4 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005886 | plasma membrane |
| GO:0005524 | ATP binding |
| GO:0046332 | SMAD binding |
| GO:0005025 | transforming growth factor beta receptor activity, type I |
| GO:0030509 | BMP signaling pathway |
| GO:0001502 | cartilage condensation |
| GO:0002063 | chondrocyte development |
| GO:0009953 | dorsal/ventral pattern formation |
| GO:0060350 | endochondral bone morphogenesis |
| GO:0006954 | inflammatory response |
| GO:0035108 | limb morphogenesis |
| GO:0043066 | negative regulation of apoptotic process |
| GO:1902731 | negative regulation of chondrocyte proliferation |
| GO:0001550 | ovarian cumulus expansion |
| GO:0030501 | positive regulation of bone mineralization |
| GO:0061036 | positive regulation of cartilage development |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors |
| GO:0045669 | positive regulation of osteoblast differentiation |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| GO:0030166 | proteoglycan biosynthetic process |
| GO:0060041 | retina development in camera-type eye |
| GO:0031290 | retinal ganglion cell axon guidance |