Gene: Cdon

Basic information

Tag Content
Uniprot ID G3V7K7
Entrez ID 50938
Genbank protein ID EDL83270.1
Genbank nucleotide ID XM_006242792.3; XM_006242791.3;
Ensembl protein ID ENSRNOP00000016247
Ensembl nucleotide ID ENSRNOG00000011789
Gene name Cell adhesion molecule-related/down-regulated by oncogenes
Gene symbol Cdon
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MHPDLGPLWK LLYVLVILCS SVSSDLAPYF ISEPLSAVQK LGRPVVLHCS AKPVTARISW 60
LHNGKRLDRN TEQIKIHRGT LTILSLNPSL SGCYQCVANN SVGAVVSGPA TVSAAALADF 120
DSSTMHVITA EEKNTGFIGC RVPESNPKAE VRYKIRGKWL MYSTGNYIIL PSGNLQILNV 180
SSKDKGSYKC AAYNPVTSEL KVEPAGRKLL VSRPSSDGFH ILHPALSQAL AVLPHSPVTL 240
ECVVSGVPAS QVYWLKDGQD ALSGSNWRRL YSHLATASID PADSGNYSCV VGNNRSGDVK 300
HVTYTVNVLE HASISKGLHD QKVSLGATVR FTCEVHGNPA PNRTWFHNAQ PIRPSSRHLT 360
EGSVLKITGV IMEDSGLYQC MADNGIGFMQ STGRLQIEQD SGQRPVIVTA PANVEVTDGD 420
FVTLSCNATG EPVPVIHWYG RHGLITSHPS QVLRSKSRKS HLFRPGDLDP EPVYLIMSQA 480
GSSSLSIQAV TWEHAGKYTC EAVNKHGSTQ SEAFLTVVPF ETNTKAEPVT PSEASQNDER 540
DPRDGSESGL LNLFPVKVHS GGVELPAEKN ASVPDAPNIL SPPQTHMPDT YTLVWRAGRD 600
GGMPINAYFV KYRKLDDGSG AVGSWHTVRV PGSESELHLT ELEPSSLYEV LMVARSAVGE 660
GQPAMLTFRT SKEKMASSKN TQASFPPVGI PKRPVTSEAS NSNFGVVLTD SSRHSGVPEA 720
PDRPTISMAS ETSVYVTWIP RANGGSPITA FKVEYKRMKS SDWLVAAEDI PPSKLSVEVR 780
SLEPGSIYKF RVIAINHYGE SFRSSASRPY QVAGFPNRFS NRPITGPHIA YTEAVSDTQI 840
MLKWTYIPSS NNNTPIQGFY IYYRPTDSDN DSDYKRDVVE GSKQWHTIGH LQPETSYDIK 900
MQCFNEGGES EFSNVMICET KVKRVPGASE YPMKELSTPP SSSGNGGNVG PATSPARSSD 960
MLYLIVGCVL GVMVLILLVF IALCLWKSRQ QSAIQKYDPP GYLYQGSEIN GQMVEYTTLS 1020
GTARINGSVH GGFLSKGSLS NGCSHLHHKG PNGVNGILNG TINGGLYSAH TSSLTRTCVE 1080
FEHPHHLVNG GAVYTAVPQM DPLECINCRN CRNNNRCFTK TNSPLPVVPV VASYPQDGLE 1140
MKPLGVMKFP VCPVSTVPDG GQIPEECLKD SVAPAPTQRT CRQDNTSDIN SDSTEDTAEF 1200
NRGDSSGHSE AEDKVFSWSP LILSPVLEDC SEKTAWSPPG PPLDGLSVVL QQAQET 1256

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCDON536011E1BHG3Bos taurusPredictionMore>>
1:1 orthologCDON102188923A0A452DT38Capra hircusPredictionMore>>
1:1 orthologCDON50937Q4KMG0Homo sapiensPredictionMore>>
1:1 orthologCdon57810Q32MD9CPOMus musculusPublicationMore>>
1:1 orthologCDON451650H2Q530Pan troglodytesPredictionMore>>
1:1 orthologCDONI3LGV0Sus scrofaPredictionMore>>
1:1 orthologCDONG1T3Q0Oryctolagus cuniculusPredictionMore>>
1:1 orthologCdon50938G3V7K7Rattus norvegicusPredictionMore>>
1:1 orthologcdon280652Q1L8D0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005887 integral component of plasma membrane
GO:0009952 anterior/posterior pattern specification
GO:0001708 cell fate specification
GO:0021987 cerebral cortex development
GO:0010172 embryonic body morphogenesis
GO:0060059 embryonic retina morphogenesis in camera-type eye
GO:0002088 lens development in camera-type eye
GO:0007520 myoblast fusion
GO:0043410 positive regulation of MAPK cascade
GO:0045663 positive regulation of myoblast differentiation
GO:2000179 positive regulation of neural precursor cell proliferation
GO:0045666 positive regulation of neuron differentiation
GO:0048643 positive regulation of skeletal muscle tissue development
GO:0051057 positive regulation of small GTPase mediated signal transduction
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0043393 regulation of protein binding
GO:0014816 skeletal muscle satellite cell differentiation
GO:0007224 smoothened signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1185 Reference proteome
KW-0677 Repeat
KW-0732 Signal
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR032983 CDO
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2

PROSITE

PROSITE ID PROSITE Term
PS50853 FN3
PS50835 IG_LIKE

Pfam

Pfam ID Pfam Term
PF00041 fn3
PF07679 I-set