Gene: CDON

Basic information

Tag Content
Uniprot ID H2Q530; A0A2J8N1C9;
Entrez ID 451650
Genbank protein ID JAA30393.1; JAA20779.1; JAA39574.1;
Genbank nucleotide ID XM_009424449.2
Ensembl protein ID ENSPTRP00000007603
Ensembl nucleotide ID ENSPTRG00000004452
Gene name Cdon homolog
Gene symbol CDON
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MHPDLGPLCT LLYVTLIILC SSVSSDLAPY FTSEPLSAVQ KLGGPVVLHC SAQPVTTRIS 60
WLHNGKTLDG NLEHIKIHQG TLTILSLNSS LLGYYQCLAN NSIGAIVSGP ATVSAAVLGD 120
FGSSTKHVIT AEEKSAGFIG CRVPESNPKA EVRYKIRGKW LKHSTENYLI LPSGNLQILN 180
VSLEDKGSYK CAAYNPVTHQ LKVEPIGRKL LVSRPSSDDF HILHPTHSQA LAVLSRSPVT 240
LECVVSGVPA SQVYWLKDGQ DIAPGSNWRR LYSHLATDSV DPADSGNYSC MAGNKSGDVK 300
YVTYMVNVLE HASISKGLQD QIVSLGATVH FTCDVHGNPA PNCTWFHNAQ PIHPSARHLT 360
AGNGLKISGV TVEDVGMYQC VADNGIGFMH STGRLEIEND GGFKPVIIMA PVSAKVADGD 420
FVTLSCNASG LPVPVIRWYD SHGLITSHPS QVLRSKSRKS QLSRPEGLNL EPVYFVMSQA 480
GASSLHIQAV TQEHAGKYIC EATNEHGTTQ AEASLMVVPF ETNTKAETVT LPDAAQNDDR 540
SKRDGSETGL LSSFPVKVHP SAVESAPEKN ASGISVPDAP IILSPPQTHT PDTYNLVWRA 600
GKDGGLPINA YFVKYRKLDD GVGMLGSWHT VRVPGSENEL HLAELEPSSL YEVLMVARSA 660
AGEGQPAMLT FRTSKEKTAS SKNTQASSPP VGIPKYPAVS EAANNNFGVV LTDSSRHSGV 720
PEAPDRPTIS TASETSVYVT WIPRANGGSP ITAFKVEYKR MRTSNWLVAA EDIPPSKLSV 780
EVRSLEPGST YKFRVIAINH YGESFRSSAS RPYQVAGFPN RFSNRPITGP HIAYTEAVSD 840
TQIMLKWTYI PSSNNNTPIQ GFYIYYRPTD SDNDSDYKRD VVEGSKQWHM IGHLQPETSY 900
DIKMQCFNEG GESEFSNVMI CETKVKRVPG ASEYPVKDLS TPPNSLGSGG NVGPATSPAR 960
SSDMLYLIVG CVLGVMVLIL MVFIAMCLWK NRQQNTIQKY DPPGYLYQGS DVNGQMVDYT 1020
TLSGASQING NVHGGFLTNG GLSSGYSHLH HKVPNGVNGI VNGSLNGGLY SGHTNSLTRT 1080
HVDFEHPHHL VNGGGMYTAV PQIDPLECVN CRNCRNNNRC FTKTNSTFSS SPLPVVPVVA 1140
PYPQDGLEMK PLSHVKVPVC LTSAVPDCGQ LPEESIKDNV EPVPTQHTCC QDIVNDVSSD 1200
GAEDPAEFSR GDSCAHSETE NNIVSWNALT APVPEGCAEK TTWSPPGIPL DSPTEVLQQP 1260
RET 1263

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCDON536011E1BHG3Bos taurusPredictionMore>>
1:1 orthologCDON102188923A0A452DT38Capra hircusPredictionMore>>
1:1 orthologCDON50937Q4KMG0Homo sapiensPredictionMore>>
1:1 orthologCdon57810Q32MD9CPOMus musculusPublicationMore>>
1:1 orthologCDON451650H2Q530Pan troglodytesPredictionMore>>
1:1 orthologCDONI3LGV0Sus scrofaPredictionMore>>
1:1 orthologCDONG1T3Q0Oryctolagus cuniculusPredictionMore>>
1:1 orthologCdon50938G3V7K7Rattus norvegicusPredictionMore>>
1:1 orthologcdon280652Q1L8D0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005887 integral component of plasma membrane
GO:0048598 embryonic morphogenesis
GO:0045663 positive regulation of myoblast differentiation
GO:0045664 regulation of neuron differentiation
GO:0007224 smoothened signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1185 Reference proteome
KW-0677 Repeat
KW-0732 Signal
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR032983 CDO
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2

PROSITE

PROSITE ID PROSITE Term
PS50853 FN3
PS50835 IG_LIKE

Pfam

Pfam ID Pfam Term
PF00041 fn3
PF07679 I-set