Gene: CDON

Basic information

Tag Content
Uniprot ID I3LGV0
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000023294
Ensembl nucleotide ID ENSSSCG00000022504
Gene name Cell adhesion associated, oncogene regulated
Gene symbol CDON
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MHPDPGLLQT LLCVTLLIMC SSVTSDLAPH FISEPLSAVQ KLGGPVVLHC SAKPVSAHIS 60
WLHNGKRLDR NVEQIKVHQG TLTILSLNPS LSGYYQCIAS NSIGAIVSGP ATISTAVLGD 120
FDSSTKDVIR AEEKGTGFIG CKVPDSNPKA EVRYKIRGKW LKRSTENYLI LPSGNLQILN 180
VSLEDKGSYK CAAFNPVTHE LKVEPIGQKL LVSRPSSDDF HILHPTPSQA LAVLSHSPVT 240
LECVVSGVPP SQVRWLKDGQ DAVPGSRWRR LYSHLAIDSI DPEDSGNYSC VVGNKSGDIK 300
NVTYMVNVLE HASISKGLQD QTVSLGATVQ FMCEVHGNPL PNRTWLHNAQ PIRPSPRHLT 360
VGSGLKITGV TMEDSGLYQC VADNGIGFMQ STGRLEIEKD SELKPVIVTA PASAKVADGD 420
SVTLFCNATG VPVPAIRWYD RHGLITGHLS QVLRSKSHLL RPGGADLEPV YFITSRAGSS 480
SLYIQAVTQD HAGKYTCEAA NEHGVTWSEV VLAVVPFETN TKAEIVIPSI PTQNNDKSDG 540
KGTELLSSFL VKEHSGAMES SEKNASGTSV PDAPIILSPP QTHTPDTYNL VWRAGKDGGL 600
PINAYFVKYR KLEDSVGMVG SWHTVRVPGS ENELHLTELE PSSLYEVLMV ARSAAGEGQP 660
AMLTFRTSKE KTTSSKNTQV SSPPVGIPKR PVVSEAADNF GVVLTDSSRH SGVPEAPDRP 720
TISTASETSV YVTWIPRANG GSPITAFKVE YKRMRTSDWL VAAEDIPPSK LSVEVRSLEP 780
GSTYKFRVIA INHYGESFRS SASRPYQVAG FPSRFSNRPI TGPHIAYTEA VSDTQIMLKW 840
TYIPSSNNNT PIQGFYIYYR PTDSDNDSDY KRDVVEGSKQ WHMIGHLQPE TSYDIKMQCF 900
NEGGESEFSN VMICETKVKR VPGASEYPVK DLSTPPNSSG SGGNVGPATS PARSSDMLYL 960
IVGCVLGVMV LILMTFIAMC LWKNRQQNTI QKYDPPGYLY QRSDVNGQMV EYTTLPSTNR 1020
INGNVHGSFS NGCSHLHHKI PSGVTGSLNG GLYSGHTSSL TRTRVDFEHP RHLVNGGGMY 1080
TAVPQTDPLE CINCRNCRNN NRCFTKTNST FSSSPLPVVP VVAPYPQDGL EMKALSHMKM 1140
AMCLASTVPD CSQSPEESIQ CDVAPRPAQH VCCQDNRSEI NSDCVEDTAE FNRGDSCVHS 1200
ETENKILSWN PLILPPVSTD CTEKTTWSSP GIPLDSPSGI LQQPQET 1247

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCDON536011E1BHG3Bos taurusPredictionMore>>
1:1 orthologCDON102188923A0A452DT38Capra hircusPredictionMore>>
1:1 orthologCDON50937Q4KMG0Homo sapiensPredictionMore>>
1:1 orthologCdon57810Q32MD9CPOMus musculusPublicationMore>>
1:1 orthologCDON451650H2Q530Pan troglodytesPredictionMore>>
1:1 orthologCDONI3LGV0Sus scrofaPredictionMore>>
1:1 orthologCDONG1T3Q0Oryctolagus cuniculusPredictionMore>>
1:1 orthologCdon50938G3V7K7Rattus norvegicusPredictionMore>>
1:1 orthologcdon280652Q1L8D0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005887 integral component of plasma membrane
GO:0009952 anterior/posterior pattern specification
GO:0001708 cell fate specification
GO:0021987 cerebral cortex development
GO:0010172 embryonic body morphogenesis
GO:0060059 embryonic retina morphogenesis in camera-type eye
GO:0002088 lens development in camera-type eye
GO:0007520 myoblast fusion
GO:0043410 positive regulation of MAPK cascade
GO:0045663 positive regulation of myoblast differentiation
GO:2000179 positive regulation of neural precursor cell proliferation
GO:0045666 positive regulation of neuron differentiation
GO:0048643 positive regulation of skeletal muscle tissue development
GO:0051057 positive regulation of small GTPase mediated signal transduction
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0043393 regulation of protein binding
GO:0014816 skeletal muscle satellite cell differentiation
GO:0007224 smoothened signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR032983 CDO
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2

PROSITE

PROSITE ID PROSITE Term
PS50853 FN3
PS50835 IG_LIKE

Pfam

Pfam ID Pfam Term
PF00041 fn3
PF07679 I-set