| Tag | Content |
|---|---|
| Uniprot ID | Q588C6 |
| Entrez ID | 317744 |
| Genbank protein ID | BAD95478.1 |
| Genbank nucleotide ID | NM_001025450.1 |
| Ensembl protein ID | ENSDARP00000053417 |
| Ensembl nucleotide ID | ENSDARG00000036791 |
| Gene name | DNA (cytosine-5-)-methyltransferase |
| Gene symbol | dnmt3bb.1 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRKEEIKKST EIVMPSNKYP SAESDKMTAT AAMNRDTSVG DGLSENDSGL EMTSENSPLT 60 PAEPPSPFCP KQNGGAASPA DESVNSIRRK RSRKRSDTEE DSAWDSSYSE EKAEVGSGCE 120 TGLRQRPRPR TIFQAGLTAH SKPRSRERGH SKEDHSDLVA SVPEGPALEL MEQDSKDSAQ 180 SSTTSTSTTE TASQPEYKDN KGFGIGELVW GKIKGFSWWP GMVVTWRATG RRQASHGMRW 240 LQWFGDGKFS EVSADKLDSI TAFPKFFNQS SYTKLASYRR AIFQALEVAS LRAEKTFPPS 300 EADSLEEQVK PMLDWAHGGF LPKGQEGLKP KENAEYCVFP LASESSTLLE SSPPEFPPSA 360 KRARLPLNKA KPGIEEVYSR EQMVNEVLKN HRSIEEFCLS CGKTRVATFH PLFEGGLCLT 420 CKDAYLENSY MYDDDGYQSY CTVCCGGREM LLCGNANCCR CICVDCLDIL VGAGAANSAR 480 NLDPWRCYMC QPLQQYGVLK KRHDWSLKLQ EFFVNDSGQE FESPKIYPAV PAEQRRPIRV 540 LSLFDGIATG YLVLRDLGFK VDLYIASEVC EDSISVGAVR HEGKIQYVHD VRNITRKNIA 600 EWGPFDMVIG GSPCNDLSIV NPARKGLYEG TGRLFFEFYR LLSEAKPKEG EDRPFFWMFE 660 NVVAMSVNDK RDISRFLECN PVMIDAIEVS AAHRARYFWG NLPGMKRPLC ASGMDKLELQ 720 DCLEHGRVAK FGKVRTITTR SNSIKQGKDQ HFPVMMNGKE DILWCTELER IFGFPVHYTD 780 VSNMGRGARQ KLLGRSWSVP VIRHLFAPLK DYFACE 816 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | DNMT3B | A0A452DST5 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | DNMT3B | 1789 | Q9UBC3 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Dnmt3b | 13436 | O88509 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | DNMT3B | 458174 | A0A2I3SYU8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | DNMT3B | A0A287ABQ3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Dnmt3b | 444985 | Q1LZ51 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | dnmt3bb.1 | 317744 | Q588C6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0003886 | DNA (cytosine-5-)-methyltransferase activity |
| GO:0003677 | DNA binding |
| GO:0046872 | metal ion binding |
| GO:0007368 | determination of left/right symmetry |
| GO:0010424 | DNA methylation on cytosine within a CG sequence |
| GO:0061484 | hematopoietic stem cell homeostasis |
| GO:0010468 | regulation of gene expression |
| GO:1902036 | regulation of hematopoietic stem cell differentiation |