Gene Page: SLC17A2
Summary ?
GeneID | 10246 |
Symbol | SLC17A2 |
Synonyms | NPT3 |
Description | solute carrier family 17 member 2 |
Reference | MIM:611049|HGNC:HGNC:10930|Ensembl:ENSG00000112337|HPRD:10232|Vega:OTTHUMG00000014413 |
Gene type | protein-coding |
Map location | 6p21.3 |
Pascal p-value | 1.827E-10 |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS | |
GSMA_I | Genome scan meta-analysis | Psr: 0.033 |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
MRPL47 | 0.82 | 0.82 |
COMMD10 | 0.81 | 0.77 |
C18orf32 | 0.79 | 0.76 |
MRPL13 | 0.79 | 0.77 |
CCNH | 0.79 | 0.78 |
PDCD10 | 0.78 | 0.80 |
ATP5C1 | 0.78 | 0.74 |
CRYZL1 | 0.77 | 0.76 |
MRPL1 | 0.76 | 0.75 |
SUCLG1 | 0.76 | 0.72 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
TENC1 | -0.46 | -0.53 |
DOCK6 | -0.45 | -0.50 |
MTSS1L | -0.43 | -0.48 |
MYH9 | -0.42 | -0.40 |
GP1BA | -0.42 | -0.45 |
FAM38A | -0.42 | -0.47 |
ITPR3 | -0.41 | -0.43 |
NOS3 | -0.41 | -0.49 |
C9orf131 | -0.41 | -0.49 |
ENG | -0.41 | -0.45 |
Section III. Gene Ontology annotation
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
---|---|---|---|---|
GO:0005436 | sodium:phosphate symporter activity | TAS | 9149941 | |
GO:0005215 | transporter activity | IEA | - | |
GO:0015293 | symporter activity | IEA | - | |
GO:0031402 | sodium ion binding | IEA | - | |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
GO:0006814 | sodium ion transport | TAS | 9149941 | |
GO:0006811 | ion transport | IEA | - | |
GO:0006796 | phosphate metabolic process | TAS | 9149941 | |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
GO:0005624 | membrane fraction | TAS | 9149941 | |
GO:0016020 | membrane | IEA | - | |
GO:0005887 | integral to plasma membrane | TAS | 9149941 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
BENPORATH CYCLING GENES | 648 | 385 | All SZGR 2.0 genes in this pathway |
KAYO AGING MUSCLE UP | 244 | 165 | All SZGR 2.0 genes in this pathway |
BOCHKIS FOXA2 TARGETS | 425 | 261 | All SZGR 2.0 genes in this pathway |
WHITFIELD CELL CYCLE G2 M | 216 | 124 | All SZGR 2.0 genes in this pathway |