Summary ?
GeneID10246
SymbolSLC17A2
SynonymsNPT3
Descriptionsolute carrier family 17 member 2
ReferenceMIM:611049|HGNC:HGNC:10930|Ensembl:ENSG00000112337|HPRD:10232|Vega:OTTHUMG00000014413
Gene typeprotein-coding
Map location6p21.3
Pascal p-value1.827E-10

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
GSMA_IGenome scan meta-analysisPsr: 0.033 

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
MRPL470.820.82
COMMD100.810.77
C18orf320.790.76
MRPL130.790.77
CCNH0.790.78
PDCD100.780.80
ATP5C10.780.74
CRYZL10.770.76
MRPL10.760.75
SUCLG10.760.72
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
TENC1-0.46-0.53
DOCK6-0.45-0.50
MTSS1L-0.43-0.48
MYH9-0.42-0.40
GP1BA-0.42-0.45
FAM38A-0.42-0.47
ITPR3-0.41-0.43
NOS3-0.41-0.49
C9orf131-0.41-0.49
ENG-0.41-0.45

Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005436sodium:phosphate symporter activityTAS9149941 
GO:0005215transporter activityIEA-
GO:0015293symporter activityIEA-
GO:0031402sodium ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006814sodium ion transportTAS9149941 
GO:0006811ion transportIEA-
GO:0006796phosphate metabolic processTAS9149941 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005624membrane fractionTAS9149941 
GO:0016020membraneIEA-
GO:0005887integral to plasma membraneTAS9149941 

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
BENPORATH CYCLING GENES 648385All SZGR 2.0 genes in this pathway
KAYO AGING MUSCLE UP 244165All SZGR 2.0 genes in this pathway
BOCHKIS FOXA2 TARGETS 425261All SZGR 2.0 genes in this pathway
WHITFIELD CELL CYCLE G2 M 216124All SZGR 2.0 genes in this pathway