Gene Page: STAM2

Summary
GeneID  10254
Symbol  STAM2
Synonyms  DKFZp564C047|Hbp|STAM2A|STAM2B
Description  signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
See related  HGNC:11358|MIM:606244|Ensembl:ENSG00000115145|HPRD:05876|
Locus tag  -
Gene type  protein-coding
Map location  2q23.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.02395 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
BBS10.850.86
PYGO20.850.87
PTPRF0.830.87
KIAA15390.830.87
GPR1350.830.86
LZTR10.820.88
NLGN30.820.82
MOGS0.820.85
ATXN20.820.85
ZMYM30.820.86
Top 10 negatively co-expressed genes
AF347015.21-0.70-0.78
AF347015.31-0.70-0.72
MT-CO2-0.70-0.72
MT-CYB-0.65-0.66
AF347015.27-0.65-0.67
AF347015.8-0.65-0.68
AF347015.33-0.64-0.65
HIGD1B-0.64-0.66
IFI27-0.63-0.61
FXYD1-0.62-0.61
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI15231747 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006886intracellular protein transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP10567358 |12218189 |15962011 
GO:0005737cytoplasmIEA-
GO:0016020membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DAZAP2KIAA0058 | MGC14319 | MGC766 | PRTBDAZ associated protein 2Two-hybridBioGRID16189514 
EPS15AF-1P | AF1P | MLLT5epidermal growth factor receptor pathway substrate 15-HPRD,BioGRID12551915 
HGSHRS | ZFYVE8hepatocyte growth factor-regulated tyrosine kinase substrateAffinity Capture-Western
Co-fractionation
Two-hybrid		BioGRID12551915 |16189514 
JAK1JAK1A | JAK1B | JTK3Janus kinase 1 (a protein tyrosine kinase)-HPRD,BioGRID10899310 |10993906 
JAK2JTK10Janus kinase 2 (a protein tyrosine kinase)-HPRD,BioGRID10899310 
JAK3JAK-3 | JAK3_HUMAN | JAKL | L-JAK | LJAKJanus kinase 3 (a protein tyrosine kinase, leukocyte)-HPRD,BioGRID10899310 
L3MBTL2H-l(3)mbt-l | L3MBTl(3)mbt-like 2 (Drosophila)Two-hybridBioGRID16189514 
STAMBPAMSH | MGC126516 | MGC126518STAM binding protein-HPRD,BioGRID10899310 
TYK2JTK1tyrosine kinase 2-HPRD,BioGRID10899310 
USP8FLJ34456 | HumORF8 | KIAA0055 | MGC129718 | UBPYubiquitin specific peptidase 8-HPRD,BioGRID13129930 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ENDOCYTOSIS 183132All SZGR genes in this pathway
KEGG_JAK_STAT_SIGNALING_PATHWAY 155105All SZGR genes in this pathway
PID_IL2_1PATHWAY 5543All SZGR genes in this pathway
REACTOME_MEMBRANE_TRAFFICKING 12974All SZGR genes in this pathway
REACTOME_SIGNALING_BY_EGFR_IN_CANCER 10980All SZGR genes in this pathway
REACTOME_EGFR_DOWNREGULATION 2514All SZGR genes in this pathway
REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT 2715All SZGR genes in this pathway
GAL_LEUKEMIC_STEM_CELL_UP 13378All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP 552347All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN 770415All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_UP 424268All SZGR genes in this pathway
MATSUDA_NATURAL_KILLER_DIFFERENTIATION 475313All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_CD1_AND_CD2_UP 8951All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN 172107All SZGR genes in this pathway
SU_TESTIS 7653All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_12HR_UP 11168All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_UP 245159All SZGR genes in this pathway
JIANG_TIP30_TARGETS_UP 4628All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN 505328All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_DN 918550All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 824528All SZGR genes in this pathway
JUBAN_TARGETS_OF_SPI1_AND_FLI1_UP 11573All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-2181191261A,m8hsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-22215221m8hsa-miR-22brainAAGCUGCCAGUUGAAGAACUGU
miR-315555611Ahsa-miR-31AGGCAAGAUGCUGGCAUAGCUG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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