SZGR2

Summary ?

GeneID	10281
Symbol	DSCR4
Synonyms	DCRB\|DSCRB
Description	Down syndrome critical region 4
Reference	MIM:604829\|HGNC:HGNC:3045\|Ensembl:ENSG00000184029\|HPRD:05318\|Vega:OTTHUMG00000086673
Gene type	protein-coding
Map location	21q22.2
Pascal p-value	0.044

Gene in Data Sources

Gene set name	Method of gene set	Description	Info
CV:PGCnp	Genome-wide Association Study	GWAS

Section I. Genetics and epigenetics annotation

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
GNL2	0.93	0.92
HNRNPA2B1	0.91	0.91
CXorf26	0.91	0.93
IK	0.91	0.93
RIOK1	0.90	0.92
CBX3	0.90	0.93
C9orf30	0.90	0.91
HTATSF1	0.90	0.92
RARS2	0.90	0.91
SNW1	0.90	0.92

Top 10 negatively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
HLA-F	-0.73	-0.81
AF347015.27	-0.71	-0.83
MT-CO2	-0.71	-0.83
AF347015.33	-0.70	-0.83
AF347015.31	-0.70	-0.83
TINAGL1	-0.69	-0.80
MT-CYB	-0.68	-0.82
TSC22D4	-0.68	-0.79
FXYD1	-0.68	-0.81
AF347015.8	-0.67	-0.82

Section V. Pathway annotation